Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEP1A
  • Mouse genes Mep1a
  • Rat genes Mep1a
  • Zfish genes mep1a.1,mep1a.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mep1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070573	metallodipeptidase activity	MEP1A	IDA		Human	PMID:22923609
Molecular Function	GO:0008237	metallopeptidase activity	MEP1A	IDA		Human	PMID:22923609
Molecular Function	GO:0005515	protein binding	MEP1A	IPI	UniProtKB:P14780	Human	PMID:23123160
Molecular Function	GO:0005515	protein binding	MEP1A	IPI	UniProtKB:Q16820	Human	PMID:9288916
Cellular Component	GO:0070062	extracellular exosome	MEP1A	HDA		Human	PMID:11487543
Cellular Component	GO:0016020	membrane	Mep1a	IDA		Mouse	PMID:8407940
Cellular Component	GO:0017090	meprin A complex	MEP1A	IDA		Human	PMID:9288916
Cellular Component	GO:0017090	meprin A complex	Mep1a	IDA		Rat	PMID:12437103|RGD:633322
Cellular Component	GO:0005886	plasma membrane	MEP1A	IDA		Human	PMID:22923609
Biological Process	GO:0038004	epidermal growth factor receptor ligand maturation	MEP1A	IDA		Human	PMID:22923609
Biological Process	GO:0045766	positive regulation of angiogenesis	mep1a.2	IMP	ZFIN:ZDB-MRPHLNO-100521-2	Zfish	PMID:20098618
Biological Process	GO:0140448	signaling receptor ligand precursor processing	MEP1A	IDA		Human	PMID:22923609

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern