Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEPE
  • Mouse genes Mepe
  • Rat genes Mepe
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mepe

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MEPE	IPI	UniProtKB:P78562	Human	PMID:15664000
Molecular Function	GO:0005515	protein binding	MEPE	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	MEPE	IPI	UniProtKB:Q2QGD7	Human	PMID:32296183
Biological Process	GO:0030282	bone mineralization	Mepe	IMP	MGI:MGI:2448895	Mouse	PMID:12421822
Biological Process	GO:0030502	negative regulation of bone mineralization	Mepe	IDA		Mouse	PMID:22766095
Biological Process	GO:0030502	negative regulation of bone mineralization	Mepe	IMP	MGI:MGI:2448895	Mouse	PMID:15843468
Biological Process	GO:0030502	negative regulation of bone mineralization	Mepe	IMP	MGI:MGI:2448895	Mouse	PMID:12421822
Biological Process	GO:0046850	regulation of bone remodeling	Mepe	IEP		Rat	PMID:10967096|RGD:70633

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern