Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MERTK
  • Mouse genes Mertk
  • Rat genes Mertk
  • Zfish genes mertka
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mertk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MERTK	IPI	UniProtKB:Q14393	Human	PMID:20103767
Cellular Component	GO:0005737	cytoplasm	MERTK	IDA		Human	PMID:18395422
Cellular Component	GO:0005737	cytoplasm	MERTK	IDA		Human	PMID:19204785
Cellular Component	GO:0005615	extracellular space	MERTK	IDA		Human	PMID:18395422
Cellular Component	GO:0001750	photoreceptor outer segment	Mertk	IDA		Rat	PMID:11861639|RGD:1299193
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IMP		Mouse	MGI:MGI:3778590|PMID:18159085
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IDA		Mouse	PMID:29440417
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:18159085
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:18159085
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:23878224
Biological Process	GO:0043277	apoptotic cell clearance	Mertk	IMP	MGI:MGI:2387768	Mouse	PMID:17442946
Biological Process	GO:0051649	establishment of localization in cell	Mertk	IMP	MGI:MGI:2387765	Mouse	PMID:15650770
Biological Process	GO:0046649	lymphocyte activation	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:11452127
Biological Process	GO:0046649	lymphocyte activation	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:11452127
Biological Process	GO:0001779	natural killer cell differentiation	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:16751775
Biological Process	GO:0001779	natural killer cell differentiation	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:16751775
Biological Process	GO:0001818	negative regulation of cytokine production	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:23878224
Biological Process	GO:2000107	negative regulation of leukocyte apoptotic process	MERTK	IMP		Human	PMID:23353780
Biological Process	GO:0051250	negative regulation of lymphocyte activation	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:11452127
Biological Process	GO:0051250	negative regulation of lymphocyte activation	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:11452127
Biological Process	GO:0097350	neutrophil clearance	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:23878224
Biological Process	GO:0006909	phagocytosis	MERTK	IMP		Human	PMID:19204785
Biological Process	GO:0006909	phagocytosis	Mertk	IDA		Rat	PMID:11861639|RGD:1299193
Biological Process	GO:0006909	phagocytosis	Mertk	IMP		Rat	PMID:11861639|RGD:1299193
Biological Process	GO:0030168	platelet activation	Mertk	IMP	MGI:MGI:2387765	Mouse	PMID:15650770
Biological Process	GO:0050766	positive regulation of phagocytosis	MERTK	IDA		Human	PMID:18395422
Biological Process	GO:0050766	positive regulation of phagocytosis	Mertk	IDA		Rat	PMID:11592982|RGD:69668
Biological Process	GO:0043491	protein kinase B signaling	Mertk	IGI	MGI:MGI:95660	Mouse	PMID:15650770
Biological Process	GO:0006468	protein phosphorylation	Mertk	IDA		Rat	PMID:11861639|RGD:1299193
Biological Process	GO:0060041	retina development in camera-type eye	Mertk	IMP		Mouse	PMID:21052544
Biological Process	GO:0032940	secretion by cell	Mertk	IMP	MGI:MGI:2387765	Mouse	PMID:15650770
Biological Process	GO:0007283	spermatogenesis	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:10227296
Biological Process	GO:0007283	spermatogenesis	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:10227296
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Mertk	IMP	MGI:MGI:2387765	Mouse	PMID:15650770
Biological Process	GO:0060068	vagina development	Mertk	IGI	MGI:MGI:1347244	Mouse	PMID:18393392
Biological Process	GO:0060068	vagina development	Mertk	IGI	MGI:MGI:104294	Mouse	PMID:18393392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern