Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MESP2
  • Mouse genes Mesp2
  • Rat genes Mesp2
  • Zfish genes mespba,mespbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mesp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mesp2	IDA		Mouse	MGI:MGI:3578712|PMID:15902259
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mesp2	IDA		Mouse	PMID:15902259
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mesp2	IDA		Mouse	MGI:MGI:3578712|PMID:15902259
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MESP2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Mesp2	IDA		Mouse	PMID:15902259
Biological Process	GO:0009952	anterior/posterior pattern specification	mespba	IMP		Zfish	PMID:10725245
Biological Process	GO:0097101	blood vessel endothelial cell fate specification	mespba	IMP		Zfish	PMID:27554166
Biological Process	GO:0097101	blood vessel endothelial cell fate specification	mespbb	IMP		Zfish	PMID:27554166
Biological Process	GO:0061371	determination of heart left/right asymmetry	mespba	IGI	ZFIN:ZDB-GENO-161206-2,ZFIN:ZDB-MRPHLNO-060113-7	Zfish	PMID:27554166
Biological Process	GO:0061371	determination of heart left/right asymmetry	mespbb	IGI	ZFIN:ZDB-GENO-161206-2,ZFIN:ZDB-MRPHLNO-161122-2	Zfish	PMID:27554166
Biological Process	GO:0008078	mesodermal cell migration	Mesp2	IGI	MGI:MGI:104659	Mouse	PMID:10887078
Biological Process	GO:0007219	Notch signaling pathway	Mesp2	IMP	MGI:MGI:3580268	Mouse	PMID:20346937
Biological Process	GO:0007219	Notch signaling pathway	Mesp2	IGI	MGI:MGI:104659	Mouse	PMID:15902259
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mesp2	IDA		Mouse	PMID:15902259
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mesp2	IMP	MGI:MGI:3580268	Mouse	PMID:20346937
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	mespba	IGI	ZFIN:ZDB-GENO-160517-1	Zfish	PMID:25725067
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	mespba	IGI	ZFIN:ZDB-MRPHLNO-060113-7,ZFIN:ZDB-MRPHLNO-150603-3	Zfish	PMID:25725067
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	mespba	IGI	ZFIN:ZDB-GENO-160517-2	Zfish	PMID:25725067
Biological Process	GO:0048641	regulation of skeletal muscle tissue development	mespbb	IGI	ZFIN:ZDB-MRPHLNO-060113-7,ZFIN:ZDB-MRPHLNO-150603-3	Zfish	PMID:25725067
Biological Process	GO:0032526	response to retinoic acid	mespba	IDA		Zfish	PMID:18261720
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Mesp2	IDA		Mouse	PMID:18462699
Biological Process	GO:0032525	somite rostral/caudal axis specification	Mesp2	IMP	MGI:MGI:3580268	Mouse	PMID:20346937
Biological Process	GO:0032525	somite rostral/caudal axis specification	mespba	IGI	ZFIN:ZDB-GENO-161208-3	Zfish	PMID:27385009
Biological Process	GO:0032525	somite rostral/caudal axis specification	mespbb	IGI	ZFIN:ZDB-GENO-161208-3	Zfish	PMID:27385009
Biological Process	GO:0001757	somite specification	mespba	IGI	ZFIN:ZDB-GENO-161208-3	Zfish	PMID:27385009
Biological Process	GO:0001757	somite specification	mespbb	IGI	ZFIN:ZDB-GENO-161208-3	Zfish	PMID:27385009
Biological Process	GO:0001756	somitogenesis	Mesp2	IMP	MGI:MGI:3580268	Mouse	PMID:15902259
Biological Process	GO:0001756	somitogenesis	Mesp2	IGI	MGI:MGI:104659	Mouse	PMID:15902259
Biological Process	GO:0001756	somitogenesis	mespba	IMP		Zfish	PMID:10725245
Biological Process	GO:0001756	somitogenesis	mespba	IMP	ZFIN:ZDB-MRPHLNO-060113-7	Zfish	PMID:16326386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern