Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METRNL
  • Mouse genes Metrnl
  • Rat genes Metrnl
  • Zfish genes metrnla,metrnlb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Metrnl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Cellular Component	GO:0070062	extracellular exosome	METRNL	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Cellular Component	GO:0005615	extracellular space	Metrnl	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Metrnl	IDA		Mouse	MGI:MGI:5551517|PMID:24393292
Biological Process	GO:0050873	brown fat cell differentiation	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Biological Process	GO:0097009	energy homeostasis	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Biological Process	GO:0045444	fat cell differentiation	Metrnl	IDA		Mouse	MGI:MGI:5551517|PMID:24393292
Biological Process	GO:0050728	negative regulation of inflammatory response	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Biological Process	GO:0009409	response to cold	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147
Biological Process	GO:0014850	response to muscle activity	Metrnl	IDA		Mouse	MGI:MGI:5574515|PMID:24906147

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern