Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL1
  • Mouse genes Mettl1
  • Rat genes Mettl1
  • Zfish genes mettl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:15861136
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:26751069
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	METTL1	IPI	UniProtKB:P57081	Human	PMID:32296183
Molecular Function	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	METTL1	IDA		Human	PMID:12403464
Molecular Function	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	METTL1	IDA		Human	PMID:15861136
Molecular Function	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	METTL1	IDA		Human	PMID:36599982
Molecular Function	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	METTL1	IDA		Human	PMID:36599985
Cellular Component	GO:0005829	cytosol	METTL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	METTL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	METTL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	METTL1	IDA		Human	PMID:15861136
Cellular Component	GO:0106143	tRNA (m7G46) methyltransferase complex	METTL1	IDA		Human	PMID:36599982
Cellular Component	GO:0106143	tRNA (m7G46) methyltransferase complex	METTL1	IDA		Human	PMID:36599985
Biological Process	GO:0106004	tRNA (guanine-N7)-methylation	METTL1	IDA		Human	PMID:36599982
Biological Process	GO:0106004	tRNA (guanine-N7)-methylation	METTL1	IDA		Human	PMID:36599985
Biological Process	GO:0006400	tRNA modification	METTL1	IDA		Human	PMID:12403464
Biological Process	GO:0006400	tRNA modification	METTL1	IDA		Human	PMID:15861136
Biological Process	GO:0036416	tRNA stabilization	METTL1	IDA		Human	PMID:36599982
Biological Process	GO:0036416	tRNA stabilization	METTL1	IDA		Human	PMID:36599985

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern