Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL22
  • Mouse genes Mettl22
  • Rat genes Mettl22
  • Zfish genes mettl22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031072	heat shock protein binding	METTL22	IPI	UniProtKB:P07900	Human	PMID:23349634
Molecular Function	GO:0031072	heat shock protein binding	METTL22	IPI	UniProtKB:P08238	Human	PMID:23349634
Molecular Function	GO:0031072	heat shock protein binding	METTL22	IPI	UniProtKB:P0DMV8	Human	PMID:23349634
Molecular Function	GO:0031072	heat shock protein binding	METTL22	IPI	UniProtKB:P0DMV9	Human	PMID:23349634
Molecular Function	GO:0005515	protein binding	METTL22	IPI	UniProtKB:O60870	Human	PMID:23349634
Molecular Function	GO:0005515	protein binding	METTL22	IPI	UniProtKB:P55072,UniProtKB:Q9BZE9	Human	PMID:23349634
Molecular Function	GO:0008276	protein methyltransferase activity	METTL22	IDA		Human	PMID:23349634
Cellular Component	GO:0005730	nucleolus	METTL22	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	METTL22	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	METTL22	IDA		Human	PMID:23349634
Cellular Component	GO:0032991	protein-containing complex	METTL22	IDA		Human	PMID:23349634
Biological Process	GO:0060218	hematopoietic stem cell differentiation	mettl22	IMP	ZFIN:ZDB-MRPHLNO-170127-3	Zfish	PMID:27797851
Biological Process	GO:0006479	protein methylation	METTL22	IDA		Human	PMID:23349634

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern