Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL4
  • Mouse genes Mettl4
  • Rat genes Mettl4
  • Zfish genes mettl4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008173	RNA methyltransferase activity	METTL4	IDA		Human	PMID:31913360
Molecular Function	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	METTL4	IDA		Human	PMID:32183942
Molecular Function	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	Mettl4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744
Cellular Component	GO:0005829	cytosol	METTL4	IDA		Human	PMID:32183942
Cellular Component	GO:0005759	mitochondrial matrix	METTL4	IDA		Human	PMID:32183942
Cellular Component	GO:0005634	nucleus	METTL4	IDA		Human	PMID:31913360
Cellular Component	GO:0005634	nucleus	METTL4	IDA		Human	PMID:32183942
Biological Process	GO:0032775	DNA methylation on adenine	METTL4	IDA		Human	PMID:32183942
Biological Process	GO:0032775	DNA methylation on adenine	Mettl4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744
Biological Process	GO:1902275	regulation of chromatin organization	Mettl4	IDA		Mouse	MGI:MGI:6323482|PMID:30982744
Biological Process	GO:0090296	regulation of mitochondrial DNA replication	METTL4	IMP		Human	PMID:32183942
Biological Process	GO:1903108	regulation of mitochondrial transcription	METTL4	IMP		Human	PMID:32183942
Biological Process	GO:0043484	regulation of RNA splicing	METTL4	IMP		Human	PMID:31913360
Biological Process	GO:0120049	snRNA (adenine-N6)-methylation	METTL4	IDA		Human	PMID:31913360

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern