Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL8
  • Mouse genes Mettl8
  • Rat genes Mettl8
  • Zfish genes mettl8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004402	histone acetyltransferase activity	Mettl8	IDA		Mouse	PMID:15992539
Molecular Function	GO:0008174	mRNA methyltransferase activity	METTL8	IMP		Human	PMID:28655767
Molecular Function	GO:0008174	mRNA methyltransferase activity	Mettl8	IMP	MGI:MGI:5903742	Mouse	PMID:28655767
Molecular Function	GO:0052735	tRNA (cytosine-3-)-methyltransferase activity	METTL8	IDA		Human	PMID:34774131
Molecular Function	GO:0052735	tRNA (cytosine-3-)-methyltransferase activity	METTL8	IDA		Human	PMID:35017528
Cellular Component	GO:0005737	cytoplasm	Mettl8	IDA		Mouse	PMID:15992539
Cellular Component	GO:0005739	mitochondrion	METTL8	IDA		Human	PMID:34774131
Cellular Component	GO:0005739	mitochondrion	METTL8	IDA		Human	PMID:35017528
Cellular Component	GO:0005634	nucleus	Mettl8	IDA		Mouse	PMID:15992539
Biological Process	GO:0045444	fat cell differentiation	Mettl8	IDA		Mouse	PMID:15992539
Biological Process	GO:0070900	mitochondrial tRNA modification	METTL8	IDA		Human	PMID:34774131
Biological Process	GO:0080009	mRNA methylation	METTL8	IMP		Human	PMID:28655767
Biological Process	GO:0080009	mRNA methylation	Mettl8	IMP	MGI:MGI:5903742	Mouse	PMID:28655767
Biological Process	GO:0070131	positive regulation of mitochondrial translation	METTL8	IDA		Human	PMID:34774131
Biological Process	GO:0070131	positive regulation of mitochondrial translation	METTL8	IDA		Human	PMID:35017528
Biological Process	GO:0007519	skeletal muscle tissue development	Mettl8	IDA		Mouse	PMID:15992539
Biological Process	GO:0106217	tRNA C3-cytosine methylation	METTL8	IDA		Human	PMID:34774131
Biological Process	GO:0106217	tRNA C3-cytosine methylation	METTL8	IDA		Human	PMID:35017528

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern