Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MFSD12
  • Mouse genes Mfsd12
  • Rat genes Mfsd12
  • Zfish genes mfsd12a,mfsd12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mfsd12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033229	cysteine transmembrane transporter activity	MFSD12	IDA		Human	PMID:33208952
Cellular Component	GO:0005770	late endosome	MFSD12	IDA		Human	PMID:29025994
Cellular Component	GO:0005765	lysosomal membrane	MFSD12	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	MFSD12	IDA		Human	PMID:29025994
Cellular Component	GO:0005764	lysosome	MFSD12	IDA		Human	PMID:33208952
Cellular Component	GO:0042470	melanosome	MFSD12	IDA		Human	PMID:33208952
Biological Process	GO:1903712	cysteine transmembrane transport	MFSD12	IDA		Human	PMID:33208952
Biological Process	GO:0001942	hair follicle development	Mfsd12	IMP	MGI:MGI:1856888	Mouse	MGI:MGI:60250
Biological Process	GO:0048022	negative regulation of melanin biosynthetic process	Mfsd12	IMP		Mouse	MGI:MGI:5912387|PMID:29025994
Biological Process	GO:0043476	pigment accumulation	mfsd12a	IMP	ZFIN:ZDB-CRISPR-180827-13	Zfish	PMID:29025994
Biological Process	GO:0043474	pigment metabolic process involved in pigmentation	MFSD12	IMP		Human	PMID:33208952
Biological Process	GO:0043474	pigment metabolic process involved in pigmentation	Mfsd12	IMP		Mouse	MGI:MGI:6492453|PMID:33208952
Biological Process	GO:0043473	pigmentation	Mfsd12	IMP	MGI:MGI:1856888	Mouse	MGI:MGI:60250
Biological Process	GO:0048021	regulation of melanin biosynthetic process	MFSD12	IMP		Human	PMID:33208952
Biological Process	GO:0048021	regulation of melanin biosynthetic process	Mfsd12	IMP		Mouse	MGI:MGI:6492453|PMID:33208952

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern