Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MGMT
  • Mouse genes Mgmt
  • Rat genes Mgmt
  • Zfish genes mgmt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mgmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Mgmt	IDA		Rat	PMID:12479403|RGD:729120
Molecular Function	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Mgmt	IDA		Rat	PMID:15025514|RGD:2316914
Molecular Function	GO:0008168	methyltransferase activity	Mgmt	IDA		Mouse	PMID:1554415
Molecular Function	GO:0008168	methyltransferase activity	Mgmt	IDA		Mouse	PMID:9560238
Cellular Component	GO:0016020	membrane	MGMT	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	MGMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mgmt	IDA		Rat	PMID:11524300|RGD:2316924
Biological Process	GO:0071479	cellular response to ionizing radiation	Mgmt	IEP		Rat	PMID:9780001|RGD:2316946
Biological Process	GO:0071407	cellular response to organic cyclic compound	Mgmt	IEP		Rat	PMID:19549930|RGD:2315566
Biological Process	GO:0034599	cellular response to oxidative stress	Mgmt	IEP		Rat	PMID:11133343|RGD:2316930
Biological Process	GO:0006974	DNA damage response	Mgmt	IMP	MGI:MGI:1857949	Mouse	PMID:10657972
Biological Process	GO:0006974	DNA damage response	Mgmt	IMP	MGI:MGI:1857949	Mouse	PMID:9560238
Biological Process	GO:0006974	DNA damage response	Mgmt	IEP		Rat	PMID:12815001|RGD:2316926
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	Mgmt	IDA		Mouse	PMID:1554415
Biological Process	GO:0006307	DNA dealkylation involved in DNA repair	Mgmt	IDA		Rat	PMID:15025514|RGD:2316914
Biological Process	GO:0006281	DNA repair	Mgmt	IMP		Mouse	PMID:13679151
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	Mgmt	IEP		Rat	PMID:16086375|RGD:2316910
Biological Process	GO:0043066	negative regulation of apoptotic process	MGMT	IDA		Human	PMID:24147153
Biological Process	GO:0045739	positive regulation of DNA repair	Mgmt	IDA		Rat	PMID:1945835|RGD:729332
Biological Process	GO:2000781	positive regulation of double-strand break repair	MGMT	IDA		Human	PMID:24147153
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Mgmt	IMP		Mouse	PMID:13679151
Biological Process	GO:0045471	response to ethanol	Mgmt	IEP		Rat	PMID:11524300|RGD:2316924
Biological Process	GO:0051593	response to folic acid	Mgmt	IEP		Rat	PMID:20051376|RGD:2316897
Biological Process	GO:0014070	response to organic cyclic compound	Mgmt	IEP		Rat	PMID:12517412|RGD:2316915
Biological Process	GO:0009636	response to toxic substance	Mgmt	IEP		Rat	PMID:20011461|RGD:2316899
Biological Process	GO:0009410	response to xenobiotic stimulus	Mgmt	IEP		Rat	PMID:19860839|RGD:2316493

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern