Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MGST1
  • Mouse genes Mgst1
  • Rat genes Mgst1
  • Zfish genes mgst1.1,mgst1.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mgst1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043295	glutathione binding	Mgst1	IDA		Rat	PMID:16806268|RGD:8553629
Molecular Function	GO:0004602	glutathione peroxidase activity	MGST1	IDA		Human	PMID:20727966
Molecular Function	GO:0004364	glutathione transferase activity	MGST1	IDA		Human	PMID:20727966
Molecular Function	GO:0004364	glutathione transferase activity	Mgst1	IDA		Mouse	PMID:10767383
Molecular Function	GO:0004364	glutathione transferase activity	Mgst1	IDA		Rat	PMID:7173206|RGD:2302292
Molecular Function	GO:0042802	identical protein binding	Mgst1	IDA		Rat	PMID:14726533|RGD:2302288
Molecular Function	GO:0042802	identical protein binding	Mgst1	IPI	RGD:70927	Rat	PMID:18634816|RGD:2302282
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:Q8WX92	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:O14798	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:O75084	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:P01133	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:P01282-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:Q14802-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST1	IPI	UniProtKB:Q96PQ1	Human	PMID:32296183
Cellular Component	GO:0045177	apical part of cell	Mgst1	IDA		Rat	PMID:9010624|RGD:2302291
Cellular Component	GO:0005783	endoplasmic reticulum	Mgst1	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0016020	membrane	Mgst1	IDA		Rat	PMID:16806268|RGD:8553629
Cellular Component	GO:0005743	mitochondrial inner membrane	Mgst1	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	MGST1	IDA		Human	PMID:20727966
Cellular Component	GO:0005739	mitochondrion	Mgst1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Mgst1	IDA		Rat	PMID:18634816|RGD:2302282
Cellular Component	GO:0005634	nucleus	Mgst1	IDA		Rat	PMID:9010624|RGD:2302291
Cellular Component	GO:0005778	peroxisomal membrane	Mgst1	IDA		Rat	PMID:16385473|RGD:2302286
Biological Process	GO:0071449	cellular response to lipid hydroperoxide	MGST1	IDA		Human	PMID:20727966
Biological Process	GO:0006749	glutathione metabolic process	Mgst1	IDA		Mouse	PMID:10767383
Biological Process	GO:0034635	glutathione transport	MGST1	IDA		Human	PMID:20727966
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mgst1.1	IMP	ZFIN:ZDB-MRPHLNO-180924-2	Zfish	PMID:29702404
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mgst1.1	IGI	ZFIN:ZDB-MRPHLNO-180924-2,ZFIN:ZDB-MRPHLNO-180924-3	Zfish	PMID:29702404
Biological Process	GO:0030097	hemopoiesis	mgst1.1	IMP	ZFIN:ZDB-MRPHLNO-180924-2	Zfish	PMID:29702404
Biological Process	GO:0030097	hemopoiesis	mgst1.1	IGI	ZFIN:ZDB-MRPHLNO-180924-2,ZFIN:ZDB-MRPHLNO-180924-3	Zfish	PMID:29702404
Biological Process	GO:0033327	Leydig cell differentiation	Mgst1	IEP		Rat	PMID:15149725|RGD:2302287
Biological Process	GO:0032496	response to lipopolysaccharide	Mgst1	IDA		Rat	PMID:18634816|RGD:2302282
Biological Process	GO:0010243	response to organonitrogen compound	Mgst1	IDA		Rat	PMID:18634816|RGD:2302282
Biological Process	GO:0009410	response to xenobiotic stimulus	Mgst1	IDA		Rat	PMID:17571305|RGD:2302284

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern