Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MGST2
  • Mouse genes Mgst2
  • Rat genes Mgst2
  • Zfish genes mgst2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mgst2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043295	glutathione binding	MGST2	IDA		Human	PMID:26066610
Molecular Function	GO:0004602	glutathione peroxidase activity	MGST2	IDA		Human	PMID:23409838
Molecular Function	GO:0004602	glutathione peroxidase activity	MGST2	IDA		Human	PMID:9278457
Molecular Function	GO:0004602	glutathione peroxidase activity	Mgst2	IDA		Rat	PMID:14637132|RGD:2302289
Molecular Function	GO:0004364	glutathione transferase activity	MGST2	IDA		Human	PMID:23409838
Molecular Function	GO:0004364	glutathione transferase activity	MGST2	IDA		Human	PMID:8703034
Molecular Function	GO:0004364	glutathione transferase activity	Mgst2	IDA		Rat	PMID:14637132|RGD:2302289
Molecular Function	GO:0042802	identical protein binding	MGST2	IDA		Human	PMID:26066610
Molecular Function	GO:0042802	identical protein binding	MGST2	IPI	UniProtKB:Q99735	Human	PMID:32296183
Molecular Function	GO:0004464	leukotriene-C4 synthase activity	MGST2	IDA		Human	PMID:23409838
Molecular Function	GO:0004464	leukotriene-C4 synthase activity	MGST2	IDA		Human	PMID:8703034
Molecular Function	GO:0004464	leukotriene-C4 synthase activity	MGST2	IDA		Human	PMID:9092565
Molecular Function	GO:0004464	leukotriene-C4 synthase activity	Mgst2	IDA		Rat	PMID:14637132|RGD:2302289
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:O75396	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:P16619	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:P78348	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q16585	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q6UWW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q86T13	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q92843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q96LL9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q9HD36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q9NRX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MGST2	IPI	UniProtKB:Q9UNK0	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Mgst2	IDA		Rat	PMID:18461660|RGD:2302283
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MGST2	IDA		Human	PMID:8703034
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MGST2	IDA		Human	PMID:9278457
Cellular Component	GO:0016020	membrane	MGST2	IDA		Human	PMID:9278457
Cellular Component	GO:0005886	plasma membrane	MGST2	IDA		Human	PMID:9092565
Biological Process	GO:0006750	glutathione biosynthetic process	MGST2	IDA		Human	PMID:8703034
Biological Process	GO:0019370	leukotriene biosynthetic process	MGST2	IDA		Human	PMID:23409838
Biological Process	GO:0019370	leukotriene biosynthetic process	MGST2	IDA		Human	PMID:8703034
Biological Process	GO:0019370	leukotriene biosynthetic process	MGST2	IDA		Human	PMID:9092565
Biological Process	GO:0006629	lipid metabolic process	MGST2	IDA		Human	PMID:9278457
Biological Process	GO:0046466	membrane lipid catabolic process	MGST2	IDA		Human	PMID:23409838
Biological Process	GO:0032496	response to lipopolysaccharide	Mgst2	IEP		Rat	PMID:18461660|RGD:2302283
Biological Process	GO:0010243	response to organonitrogen compound	Mgst2	IEP		Rat	PMID:17496435|RGD:2302285

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern