Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MIB1
  • Mouse genes Mib1
  • Rat genes Mib1
  • Zfish genes mib1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mib1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	mib1	IPI	ZFIN:ZDB-GENE-030404-2	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:Q9QYP6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:Q9UHD2	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:O95166	Human	PMID:28712572
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:P0DTD1:PRO_0000449627	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:P0DTD1:PRO_0000449627	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	MIB1	IPI	UniProtKB:P0DTD1:PRO_0000449627	Human	PMID:34232536
Molecular Function	GO:0005515	protein binding	Mib1	IPI	UniProtKB:Q8IY22	Mouse	MGI:MGI:5512952|PMID:20018188
Molecular Function	GO:0005515	protein binding	Mib1	IPI	UniProtKB:Q61483	Mouse	MGI:MGI:5306864|PMID:21985982
Molecular Function	GO:0005515	protein binding	Mib1	IPI	PR:O88516	Mouse	PMID:16000382
Molecular Function	GO:0005515	protein binding	Mib1	IPI	PR:Q9QXX0	Mouse	PMID:16000382
Molecular Function	GO:0005515	protein binding	Mib1	IPI	PR:Q9QYE5	Mouse	PMID:16000382
Molecular Function	GO:0005515	protein binding	Mib1	IPI	PR:Q61483	Mouse	PMID:16000382
Molecular Function	GO:0005515	protein binding	Mib1	IPI	PR:Q9JI71	Mouse	PMID:16000382
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-061110-94	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib1	IPI	RefSeq:NP_571030	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-980526-29	Zfish	PMID:15013799
Molecular Function	GO:0005515	protein binding	mib1	IPI	RefSeq:NP_571029	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-061019-1	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-030131-726	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-050628-1	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-030826-19	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib1	IPI	RefSeq:NP_571019	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-990415-47	Zfish	PMID:26020642
Molecular Function	GO:0005515	protein binding	mib1	IPI	ZFIN:ZDB-GENE-990415-47	Zfish	PMID:15013799
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	mib1	IDA		Zfish	PMID:17196985
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	mib1	IDA		Zfish	PMID:15013799
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	mib1	IGI	ZFIN:ZDB-GENE-050628-1	Zfish	PMID:17196985
Cellular Component	GO:0005813	centrosome	MIB1	IDA		Human	PMID:21399614
Cellular Component	GO:0005737	cytoplasm	mib1	IDA		Zfish	PMID:15013799
Cellular Component	GO:0005737	cytoplasm	mib1	IDA		Zfish	PMID:17196985
Cellular Component	GO:0031410	cytoplasmic vesicle	Mib1	IDA		Mouse	PMID:16000382
Cellular Component	GO:0031410	cytoplasmic vesicle	mib1	IDA		Zfish	PMID:17331493
Cellular Component	GO:0030139	endocytic vesicle	mib1	IDA		Zfish	PMID:15013799
Cellular Component	GO:0048471	perinuclear region of cytoplasm	mib1	IGI	ZFIN:ZDB-GENE-990415-47	Zfish	PMID:17196985
Cellular Component	GO:0048471	perinuclear region of cytoplasm	mib1	IGI	ZFIN:ZDB-GENE-000125-4	Zfish	PMID:17196985
Cellular Component	GO:0014069	postsynaptic density	Mib1	IDA		Rat	PMID:17728463|RGD:2302293
Cellular Component	GO:0032991	protein-containing complex	mib1	IPI	ZFIN:ZDB-GENE-030616-450	Zfish	PMID:21262462
Biological Process	GO:0048899	anterior lateral line development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0001568	blood vessel development	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0001568	blood vessel development	mib1	IGI	ZFIN:ZDB-GENO-210922-2,ZFIN:ZDB-MRPHLNO-210311-1,ZFIN:ZDB-MRPHLNO-070509-1,ZFIN:ZDB-MRPHLNO-051121-1	Zfish	PMID:30656567
Biological Process	GO:0001568	blood vessel development	mib1	IMP	ZFIN:ZDB-GENO-050209-22	Zfish	PMID:17251261
Biological Process	GO:0048514	blood vessel morphogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:11585794
Biological Process	GO:0007420	brain development	mib1	IMP	ZFIN:ZDB-GENO-120606-1	Zfish	PMID:21688347
Biological Process	GO:0007417	central nervous system development	mib1	IMP	ZFIN:ZDB-GENO-980202-241	Zfish	PMID:9007234
Biological Process	GO:0007417	central nervous system development	mib1	IMP	ZFIN:ZDB-GENO-980202-199	Zfish	PMID:9007234
Biological Process	GO:0060216	definitive hemopoiesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:25714926
Biological Process	GO:0007368	determination of left/right symmetry	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17199043
Biological Process	GO:0048066	developmental pigmentation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007256
Biological Process	GO:0021536	diencephalon development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:21148001
Biological Process	GO:0048546	digestive tract morphogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15689380
Biological Process	GO:0031076	embryonic camera-type eye development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15680358
Biological Process	GO:0009880	embryonic pattern specification	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15366005
Biological Process	GO:0001885	endothelial cell development	mib1	IMP	ZFIN:ZDB-GENO-050209-22	Zfish	PMID:17251261
Biological Process	GO:0002064	epithelial cell development	mib1	IMP	ZFIN:ZDB-GENO-070730-2	Zfish	PMID:19705151
Biological Process	GO:0002064	epithelial cell development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:19705151
Biological Process	GO:0021508	floor plate formation	mib1	IMP	ZFIN:ZDB-GENO-980202-1208	Zfish	PMID:17045256
Biological Process	GO:0048859	formation of anatomical boundary	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0048699	generation of neurons	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17199043
Biological Process	GO:0048699	generation of neurons	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0010001	glial cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-020426-41	Zfish	PMID:15013799
Biological Process	GO:0021986	habenula development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17199043
Biological Process	GO:0035315	hair cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9806913
Biological Process	GO:0007507	heart development	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0007507	heart development	mib1	IMP	ZFIN:ZDB-GENO-130419-6	Zfish	PMID:23314057
Biological Process	GO:0001947	heart looping	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:25714926
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	mib1	IGI	ZFIN:ZDB-GENE-040426-780	Zfish	PMID:25714926
Biological Process	GO:0060218	hematopoietic stem cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-090730-4	Zfish	PMID:19332767
Biological Process	GO:0030097	hemopoiesis	mib1	IMP	ZFIN:ZDB-MRPHLNO-051121-1	Zfish	PMID:16166372
Biological Process	GO:0030097	hemopoiesis	mib1	IMP	ZFIN:ZDB-MRPHLNO-070730-7	Zfish	PMID:25490269
Biological Process	GO:0030902	hindbrain development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0030902	hindbrain development	mib1	IMP	ZFIN:ZDB-GENO-070730-2	Zfish	PMID:19705151
Biological Process	GO:0030902	hindbrain development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:19705151
Biological Process	GO:0030902	hindbrain development	mib1	IMP	ZFIN:ZDB-GENO-980202-241	Zfish	PMID:9007238
Biological Process	GO:0001701	in utero embryonic development	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0060113	inner ear receptor cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:10572043
Biological Process	GO:0048892	lateral line nerve development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0030318	melanocyte differentiation	mib1	IMP	ZFIN:ZDB-GENO-070730-1	Zfish	PMID:17331493
Biological Process	GO:0030318	melanocyte differentiation	mib1	IMP	ZFIN:ZDB-GENO-070730-2	Zfish	PMID:17331493
Biological Process	GO:0030318	melanocyte differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17331493
Biological Process	GO:0030318	melanocyte differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0045665	negative regulation of neuron differentiation	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0003407	neural retina development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:25106852
Biological Process	GO:0001841	neural tube formation	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0022008	neurogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-241	Zfish	PMID:9007238
Biological Process	GO:0048666	neuron development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0030182	neuron differentiation	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0030182	neuron differentiation	mib1	IMP	ZFIN:ZDB-GENO-020426-41	Zfish	PMID:15013799
Biological Process	GO:0048663	neuron fate commitment	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9806913
Biological Process	GO:0048665	neuron fate specification	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0007219	Notch signaling pathway	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0007219	Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9806913
Biological Process	GO:0007219	Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15680358
Biological Process	GO:0007219	Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:23840804
Biological Process	GO:0007219	Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-980202-199	Zfish	PMID:17287248
Biological Process	GO:0060035	notochord cell development	mib1	IMP	ZFIN:ZDB-GENO-980202-241	Zfish	PMID:9007234
Biological Process	GO:0060035	notochord cell development	mib1	IMP	ZFIN:ZDB-GENO-980202-199	Zfish	PMID:9007234
Biological Process	GO:0030903	notochord development	mib1	IMP	ZFIN:ZDB-GENO-980202-199	Zfish	PMID:9007234
Biological Process	GO:0030903	notochord development	mib1	IMP	ZFIN:ZDB-GENO-980202-241	Zfish	PMID:9007234
Biological Process	GO:0003408	optic cup formation involved in camera-type eye development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0071599	otic vesicle development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9806913
Biological Process	GO:0071599	otic vesicle development	mib1	IMP		Zfish	PMID:9007247
Biological Process	GO:0050931	pigment cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007256
Biological Process	GO:0008284	positive regulation of cell population proliferation	mib1	IGI	ZFIN:ZDB-GENO-050811-1,ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15944187
Biological Process	GO:0045807	positive regulation of endocytosis	Mib1	IDA		Mouse	PMID:16000382
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-071218-1	Zfish	PMID:17685488
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-020426-41	Zfish	PMID:15013799
Biological Process	GO:0031398	positive regulation of protein ubiquitination	mib1	IPI	ZFIN:ZDB-GENE-061110-94	Zfish	PMID:24714733
Biological Process	GO:0031398	positive regulation of protein ubiquitination	mib1	IPI	ZFIN:ZDB-GENE-030826-19	Zfish	PMID:24714733
Biological Process	GO:0048916	posterior lateral line development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	mib1	IGI	ZFIN:ZDB-GENE-110208-9	Zfish	PMID:29078376
Biological Process	GO:0039022	pronephric duct development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0048793	pronephros development	mib1	IMP	ZFIN:ZDB-GENO-980202-199	Zfish	PMID:17287248
Biological Process	GO:0051865	protein autoubiquitination	mib1	IMP		Zfish	PMID:17196985
Biological Process	GO:0051865	protein autoubiquitination	mib1	IDA		Zfish	PMID:17196985
Biological Process	GO:0016567	protein ubiquitination	mib1	IDA		Zfish	PMID:17196985
Biological Process	GO:0016567	protein ubiquitination	mib1	IDA		Zfish	PMID:15013799
Biological Process	GO:0045685	regulation of glial cell differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15680358
Biological Process	GO:0045664	regulation of neuron differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:15068793
Biological Process	GO:0008593	regulation of Notch signaling pathway	mib1	IMP	ZFIN:ZDB-GENO-120606-1	Zfish	PMID:21688347
Biological Process	GO:0002090	regulation of receptor internalization	mib1	IDA		Zfish	PMID:17196985
Biological Process	GO:0048259	regulation of receptor-mediated endocytosis	mib1	IMP	ZFIN:ZDB-GENO-090924-1	Zfish	PMID:19056830
Biological Process	GO:0048259	regulation of receptor-mediated endocytosis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:19056830
Biological Process	GO:0021654	rhombomere boundary formation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:19705151
Biological Process	GO:0021654	rhombomere boundary formation	mib1	IMP	ZFIN:ZDB-GENO-070730-2	Zfish	PMID:19705151
Biological Process	GO:0021546	rhombomere development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0001756	somitogenesis	Mib1	IMP	MGI:MGI:3603514	Mouse	PMID:16000382
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:16225858
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007237
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17331493
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:20637620
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-070730-2	Zfish	PMID:17331493
Biological Process	GO:0001756	somitogenesis	mib1	IMP	ZFIN:ZDB-GENO-070730-1	Zfish	PMID:17331493
Biological Process	GO:0021519	spinal cord association neuron specification	mib1	IMP	ZFIN:ZDB-GENO-071004-2	Zfish	PMID:17442701
Biological Process	GO:0021510	spinal cord development	mib1	IMP	ZFIN:ZDB-GENO-130402-4	Zfish	PMID:23409159
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	mib1	IMP	ZFIN:ZDB-GENO-071004-2	Zfish	PMID:17442701
Biological Process	GO:0002040	sprouting angiogenesis	mib1	IGI	ZFIN:ZDB-MRPHLNO-051121-1,ZFIN:ZDB-MRPHLNO-140108-1,ZFIN:ZDB-MRPHLNO-170302-2	Zfish	PMID:26825552
Biological Process	GO:0061195	taste bud formation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:21791527
Biological Process	GO:0061551	trigeminal ganglion development	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:9007241
Biological Process	GO:0070086	ubiquitin-dependent endocytosis	mib1	IPI	ZFIN:ZDB-GENE-990415-47	Zfish	PMID:26020642
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	MIB1	IDA		Human	PMID:23615451
Biological Process	GO:0001570	vasculogenesis	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:18377889
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	mib1	IMP	ZFIN:ZDB-MRPHLNO-051121-1	Zfish	PMID:24768892
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:24768892
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:18680739
Biological Process	GO:0021521	ventral spinal cord interneuron specification	mib1	IMP	ZFIN:ZDB-GENO-980202-1107	Zfish	PMID:17045256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern