Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MIB2
  • Mouse genes Mib2
  • Rat genes Mib2
  • Zfish genes mib2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mib2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	mib2	IPI	ZFIN:ZDB-GENE-050628-1	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	MIB2	IPI	UniProtKB:Q9UHD2	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	Mib2	IPI	PR:A2AFI6	Mouse	PMID:34635817
Molecular Function	GO:0005515	protein binding	Mib2	IPI	PR:O35516	Mouse	PMID:34635817
Molecular Function	GO:0005515	protein binding	mib2	IPI	ZFIN:ZDB-GENE-030826-19	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib2	IPI	ZFIN:ZDB-GENE-030131-726	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib2	IPI	RefSeq:NP_571029	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib2	IPI	RefSeq:NP_775393	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib2	IPI	ZFIN:ZDB-GENE-061110-94	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib2	IPI	ZFIN:ZDB-GENE-061019-1	Zfish	PMID:24714733
Molecular Function	GO:0005515	protein binding	mib2	IPI	RefSeq:NP_571019	Zfish	PMID:17196985
Molecular Function	GO:0005515	protein binding	mib2	IPI	RefSeq:NP_571030	Zfish	PMID:17196985
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Mib2	IDA		Mouse	PMID:15824097
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MIB2	EXP		Human	PMID:31366726
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MIB2	EXP		Human	PMID:33469115
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Mib2	IDA		Mouse	PMID:34635817
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	mib2	IDA		Zfish	PMID:17196985
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	mib2	IGI	RefSeq:NP_775393	Zfish	PMID:17196985
Cellular Component	GO:0005737	cytoplasm	mib2	IDA		Zfish	PMID:17196985
Cellular Component	GO:0031410	cytoplasmic vesicle	mib2	IDA		Zfish	PMID:17331493
Cellular Component	GO:0005769	early endosome	Mib2	IDA		Mouse	PMID:15824097
Cellular Component	GO:0048471	perinuclear region of cytoplasm	mib2	IGI	ZFIN:ZDB-GENE-000125-4	Zfish	PMID:17196985
Cellular Component	GO:0005886	plasma membrane	Mib2	IDA		Mouse	PMID:34635817
Cellular Component	GO:0000151	ubiquitin ligase complex	Mib2	IDA		Mouse	PMID:15824097
Biological Process	GO:0030318	melanocyte differentiation	mib2	IMP	ZFIN:ZDB-MRPHLNO-070730-8	Zfish	PMID:17331493
Biological Process	GO:0030318	melanocyte differentiation	mib2	IMP	ZFIN:ZDB-MRPHLNO-070730-9	Zfish	PMID:17331493
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	MIB2	HMP		Human	PMID:12761501
Biological Process	GO:0031398	positive regulation of protein ubiquitination	mib2	IPI	ZFIN:ZDB-GENE-030826-19	Zfish	PMID:24714733
Biological Process	GO:0031398	positive regulation of protein ubiquitination	mib2	IPI	ZFIN:ZDB-GENE-061110-94	Zfish	PMID:24714733
Biological Process	GO:0051865	protein autoubiquitination	mib2	IDA		Zfish	PMID:17196985
Biological Process	GO:0016567	protein ubiquitination	Mib2	IDA		Mouse	PMID:15824097
Biological Process	GO:0016567	protein ubiquitination	Mib2	IDA		Mouse	PMID:34635817
Biological Process	GO:0016567	protein ubiquitination	mib2	IDA		Zfish	PMID:17196985
Biological Process	GO:0002090	regulation of receptor internalization	mib2	IDA		Zfish	PMID:17196985

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern