Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MICALL2
  • Mouse genes Micall2
  • Rat genes Micall2
  • Zfish genes micall2a,micall2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Micall2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Micall2	IDA		Mouse	MGI:MGI:5514064|PMID:23890175
Molecular Function	GO:0051015	actin filament binding	Micall2	IDA		Mouse	MGI:MGI:3794927|PMID:18332111
Molecular Function	GO:0042805	actinin binding	Micall2	IPI	UniProtKB:P57780|UniProtKB:Q7TPR4	Mouse	MGI:MGI:5514064|PMID:23890175
Molecular Function	GO:0031005	filamin binding	MICALL2	IDA		Human	PMID:23890175
Molecular Function	GO:0031005	filamin binding	Micall2	IDA		Mouse	MGI:MGI:5514064|PMID:23890175
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:P12814	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:P35609	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:P35609	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:O43707	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:P12814	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:P35609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:Q01850	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:Q08043	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MICALL2	IPI	UniProtKB:Q9UHG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Micall2	IPI	UniProtKB:P57780	Mouse	MGI:MGI:3794927|PMID:18332111
Molecular Function	GO:0005515	protein binding	Micall2	IPI	UniProtKB:P51153	Mouse	MGI:MGI:3656449|PMID:16525024
Molecular Function	GO:0005515	protein binding	Micall2	IPI	UniProtKB:P51153	Mouse	MGI:MGI:3794927|PMID:18332111
Molecular Function	GO:0031267	small GTPase binding	Micall2	IPI	UniProtKB:P55258	Mouse	MGI:MGI:5508599|PMID:18094055
Molecular Function	GO:0031267	small GTPase binding	Micall2	IPI	UniProtKB:F1PTE3|UniProtKB:P61028	Mouse	MGI:MGI:5508599|PMID:18094055
Molecular Function	GO:0031267	small GTPase binding	Micall2	IPI	UniProtKB:P51153	Mouse	MGI:MGI:5508574|PMID:20008558
Cellular Component	GO:0032432	actin filament bundle	Micall2	IDA		Mouse	PMID:16525024
Cellular Component	GO:0005923	bicellular tight junction	Micall2	IDA		Mouse	PMID:16525024
Cellular Component	GO:0005911	cell-cell junction	Micall2	IDA		Mouse	MGI:MGI:3794927|PMID:18332111
Cellular Component	GO:0043005	neuron projection	Micall2	IDA		Rat	PMID:20008558|RGD:8553724
Cellular Component	GO:0005886	plasma membrane	Micall2	IDA		Mouse	MGI:MGI:5508599|PMID:18094055
Cellular Component	GO:0055037	recycling endosome	Micall2	IDA		Mouse	MGI:MGI:5508599|PMID:18094055
Cellular Component	GO:0001725	stress fiber	Micall2	IDA		Mouse	MGI:MGI:5514064|PMID:23890175
Biological Process	GO:0031532	actin cytoskeleton reorganization	Micall2	IMP		Mouse	MGI:MGI:5514064|PMID:23890175
Biological Process	GO:0030041	actin filament polymerization	Micall2	IMP		Mouse	MGI:MGI:5508574|PMID:20008558
Biological Process	GO:0030041	actin filament polymerization	Micall2	IMP		Rat	PMID:20008558|RGD:8553724
Biological Process	GO:0070830	bicellular tight junction assembly	Micall2	IMP		Mouse	MGI:MGI:5508599|PMID:18094055
Biological Process	GO:0032456	endocytic recycling	Micall2	IMP		Mouse	MGI:MGI:5508599|PMID:18094055
Biological Process	GO:0032456	endocytic recycling	Micall2	IDA		Mouse	PMID:16525024
Biological Process	GO:0031175	neuron projection development	Micall2	IMP		Mouse	MGI:MGI:5508574|PMID:20008558
Biological Process	GO:0031175	neuron projection development	Micall2	IMP		Rat	PMID:20008558|RGD:8553724
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	MICALL2	HMP		Human	PMID:24270810
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Micall2	IMP		Mouse	MGI:MGI:5514064|PMID:23890175
Biological Process	GO:0036269	swimming behavior	micall2b	IMP	ZFIN:ZDB-MRPHLNO-180817-1	Zfish	PMID:28416812

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern