Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MID2
  • Mouse genes Mid2
  • Rat genes Mid2
  • Zfish genes mid2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mid2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	MID2	IPI	UniProtKB:O15344	Human	PMID:11806752
Molecular Function	GO:0008017	microtubule binding	MID2	IMP		Human	PMID:11806752
Molecular Function	GO:0051219	phosphoprotein binding	MID2	IPI	UniProtKB:Q61249	Human	PMID:11806752
Molecular Function	GO:0042803	protein homodimerization activity	MID2	IDA		Human	PMID:11806752
Molecular Function	GO:0003713	transcription coactivator activity	MID2	IDA		Human	PMID:23077300
Cellular Component	GO:0070062	extracellular exosome	MID2	HDA		Human	PMID:19056867
Cellular Component	GO:0005874	microtubule	MID2	IDA		Human	PMID:10400986
Cellular Component	GO:0005874	microtubule	MID2	IDA		Human	PMID:11806752
Biological Process	GO:0045087	innate immune response	MID2	IDA		Human	PMID:18248090
Biological Process	GO:0046597	negative regulation of viral entry into host cell	MID2	IDA		Human	PMID:18248090
Biological Process	GO:0032897	negative regulation of viral transcription	MID2	IDA		Human	PMID:18248090
Biological Process	GO:0010508	positive regulation of autophagy	MID2	IMP		Human	PMID:26347139
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	MID2	IMP		Human	PMID:23077300
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	MID2	IDA		Human	PMID:23077300
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	MID2	IMP		Human	PMID:23077300
Biological Process	GO:0035372	protein localization to microtubule	MID2	IMP		Human	PMID:11806752
Biological Process	GO:0044790	suppression of viral release by host	MID2	IDA		Human	PMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern