Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mixl1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MIXL1
- Mouse genes Mixl1
- Rat genes Mixl1
- Zfish genes mixl1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mixl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mixl1	IDA		Mouse	MGI:MGI:5448504\|PMID:22265737
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mixl1	IDA		Mouse	MGI:MGI:5448529\|PMID:19711456
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mixl1	IDA		Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mixl1	IDA		Mouse	MGI:MGI:5448504\|PMID:22265737
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	mixl1	IMP	ZFIN:ZDB-MRPHLNO-051205-3	Zfish	PMID:29275993
Molecular Function	GO:0042802	identical protein binding	Mixl1	IPI	UniProtKB:Q9WUI0	Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:0005515	protein binding	Mixl1	IPI	UniProtKB:P20293	Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:0005515	protein binding	mixl1	IPI	UniProtKB:Q9W6U0	Zfish	PMID:16198294
Molecular Function	GO:0005515	protein binding	mixl1	IPI	UniProtKB:Q9DDU3	Zfish	PMID:16198294
Molecular Function	GO:0042803	protein homodimerization activity	Mixl1	IPI	UniProtKB:Q9WUI0	Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mixl1	IDA		Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	mixl1	IDA		Zfish	PMID:29275993
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	mixl1	IMP	ZFIN:ZDB-MRPHLNO-051205-3	Zfish	PMID:29275993
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MIXL1	IPI	UniProtKB:O15178	Human	PMID:22164283
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Mixl1	IPI	UniProtKB:O54839\|UniProtKB:P20293\|UniProtKB:P70324\|UniProtKB:P70327\|UniProtKB:Q9ES03	Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MIXL1	IDA		Human	PMID:28473536
Cellular Component	GO:0000785	chromatin	Mixl1	IDA		Mouse	MGI:MGI:5448504\|PMID:22265737
Cellular Component	GO:0000785	chromatin	Mixl1	IDA		Mouse	MGI:MGI:5448529\|PMID:19711456
Cellular Component	GO:0000785	chromatin	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Cellular Component	GO:0000785	chromatin	Mixl1	IDA		Mouse	MGI:MGI:5448510\|PMID:22164283
Cellular Component	GO:0000785	chromatin	mixl1	IDA		Zfish	PMID:29275993
Cellular Component	GO:0005654	nucleoplasm	MIXL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mixl1	IDA		Mouse	MGI:MGI:5520048\|PMID:12619131
Cellular Component	GO:0005634	nucleus	Mixl1	IDA		Mouse	PMID:16403910
Biological Process	GO:0042074	cell migration involved in gastrulation	Mixl1	IMP	MGI:MGI:2387829	Mouse	PMID:17151016
Biological Process	GO:0048565	digestive tract development	Mixl1	IMP	MGI:MGI:2387828	Mouse	PMID:12117810
Biological Process	GO:0035050	embryonic heart tube development	mixl1	IMP	ZFIN:ZDB-GENO-980202-548	Zfish	PMID:16672336
Biological Process	GO:0009880	embryonic pattern specification	mixl1	IMP	ZFIN:ZDB-GENO-980202-548	Zfish	PMID:12889061
Biological Process	GO:0007492	endoderm development	Mixl1	IMP	MGI:MGI:2387828	Mouse	PMID:12117810
Biological Process	GO:0007492	endoderm development	mixl1	IGI	ZFIN:ZDB-GENE-990415-198,ZFIN:ZDB-GENO-070301-1	Zfish	PMID:17026981
Biological Process	GO:0001706	endoderm formation	Mixl1	IMP	MGI:MGI:2387829	Mouse	PMID:17151016
Biological Process	GO:0001706	endoderm formation	mixl1	IMP	ZFIN:ZDB-GENO-070301-1	Zfish	PMID:10817762
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-GENO-110502-3	Zfish	PMID:11092818
Biological Process	GO:0001706	endoderm formation	mixl1	IMP	ZFIN:ZDB-MRPHLNO-051205-3	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-GENE-001228-1,ZFIN:ZDB-GENE-980526-340,ZFIN:ZDB-MRPHLNO-050818-2	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	mixl1	IMP	ZFIN:ZDB-GENO-980202-548	Zfish	PMID:16672336
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-MRPHLNO-051112-1,ZFIN:ZDB-MRPHLNO-051112-3,ZFIN:ZDB-MRPHLNO-051112-4,ZFIN:ZDB-MRPHLNO-051205-3	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	mixl1	IMP	ZFIN:ZDB-GENO-980202-548	Zfish	PMID:11092818
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-GENE-001228-1	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-GENE-001228-1,ZFIN:ZDB-GENE-980526-340	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	mixl1	IMP	ZFIN:ZDB-GENO-100105-5	Zfish	PMID:10817762
Biological Process	GO:0001706	endoderm formation	mixl1	IGI	ZFIN:ZDB-GENE-980526-340	Zfish	PMID:16198294
Biological Process	GO:0035987	endodermal cell differentiation	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Biological Process	GO:0007369	gastrulation	Mixl1	IMP	MGI:MGI:2387828	Mouse	PMID:12117810
Biological Process	GO:0007507	heart development	Mixl1	IMP	MGI:MGI:2387828	Mouse	PMID:12117810
Biological Process	GO:0003007	heart morphogenesis	mixl1	IMP	ZFIN:ZDB-GENO-070301-1	Zfish	PMID:12397099
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Mixl1	IDA		Mouse	MGI:MGI:5448529\|PMID:19711456
Biological Process	GO:0030097	hemopoiesis	Mixl1	IDA		Mouse	PMID:16403910
Biological Process	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Biological Process	GO:2000382	positive regulation of mesoderm development	Mixl1	IDA		Mouse	MGI:MGI:5448529\|PMID:19711456
Biological Process	GO:2000382	positive regulation of mesoderm development	Mixl1	IDA		Mouse	PMID:16403910
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mixl1	IDA		Mouse	MGI:MGI:5447921\|PMID:19038793
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mixl1	IDA		Mouse	MGI:MGI:5448504\|PMID:22265737
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mixl1	IDA		Mouse	MGI:MGI:5448529\|PMID:19711456
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mixl1	IDA		Mouse	MGI:MGI:5448510\|PMID:22164283
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	mixl1	IMP	ZFIN:ZDB-MRPHLNO-051205-3	Zfish	PMID:29275993

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.