Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MKRN2
  • Mouse genes Mkrn2
  • Rat genes Mkrn2
  • Zfish genes mkrn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mkrn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P0C6X7:PRO_0000037311	Human	PMID:22046132
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:E9KL35	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P51668	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q9NX04	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q9Y2X8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:O00303	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P63244	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q9Y2X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MKRN2	IPI	UniProtKB:P0DTD1:PRO_0000449621	Human	PMID:32838362
Molecular Function	GO:0005515	protein binding	Mkrn2	IPI	UniProtKB:Q04207|UniProtKB:Q8R1G6	Mouse	MGI:MGI:6296023|PMID:28378844
Molecular Function	GO:0003723	RNA binding	MKRN2	HDA		Human	PMID:22681889
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Mkrn2	IDA		Mouse	MGI:MGI:6296023|PMID:28378844
Cellular Component	GO:0005737	cytoplasm	Mkrn2	IDA		Mouse	MGI:MGI:6296023|PMID:28378844
Cellular Component	GO:0005634	nucleus	Mkrn2	IDA		Mouse	MGI:MGI:6296023|PMID:28378844
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	Mkrn2	IMP		Mouse	MGI:MGI:6296023|PMID:28378844
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Mkrn2	IDA		Mouse	MGI:MGI:6296023|PMID:28378844
Biological Process	GO:0010842	retina layer formation	mkrn2	IGI	ZFIN:ZDB-MRPHLNO-120406-2,ZFIN:ZDB-MRPHLNO-120406-3,ZFIN:ZDB-GENO-210330-4	Zfish	PMID:32460013
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Mkrn2	IDA		Mouse	MGI:MGI:6296023|PMID:28378844

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern