Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MKS1
  • Mouse genes Mks1
  • Rat genes Mks1
  • Zfish genes mks1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mks1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MKS1	IPI	UniProtKB:Q5HYA8	Human	PMID:17185389
Molecular Function	GO:0005515	protein binding	MKS1	IPI	UniProtKB:Q5HYA8	Human	PMID:19515853
Molecular Function	GO:0005515	protein binding	MKS1	IPI	UniProtKB:Q6UX40	Human	PMID:26595381
Molecular Function	GO:0005515	protein binding	MKS1	IPI	UniProtKB:Q9BPU9	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	MKS1	IPI	UniProtKB:Q9BPU9	Human	PMID:32726168
Molecular Function	GO:0005515	protein binding	Mks1	IPI	UniProtKB:Q3UK10	Mouse	MGI:MGI:5298320|PMID:21763481
Molecular Function	GO:0005515	protein binding	Mks1	IPI	UniProtKB:Q8BZ64|UniProtKB:Q8K3E5|UniProtKB:Q8R2Q6|UniProtKB:Q9R1S0	Mouse	MGI:MGI:5013991|PMID:21565611
Molecular Function	GO:0005515	protein binding	Mks1	IPI	UniProtKB:Q3UK10|UniProtKB:Q9R1S0	Mouse	MGI:MGI:5298320|PMID:21763481
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q3UK10	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q8CFW7	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q8K3E5	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q922M3	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q8BZ64	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q3U284	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q8K0U3	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q9R1S0	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Mks1	IPI	PR:Q2MV57	Mouse	PMID:22179047
Cellular Component	GO:0005814	centriole	Mks1	IDA		Mouse	PMID:29038301
Cellular Component	GO:0005814	centriole	Mks1	IDA		Mouse	PMID:24302887
Cellular Component	GO:0005813	centrosome	MKS1	IDA		Human	PMID:19208769
Cellular Component	GO:0005813	centrosome	MKS1	IDA		Human	PMID:19515853
Cellular Component	GO:0005813	centrosome	Mks1	IDA		Mouse	PMID:21045211
Cellular Component	GO:0036064	ciliary basal body	MKS1	IDA		Human	PMID:19208769
Cellular Component	GO:0036064	ciliary basal body	MKS1	IDA		Human	PMID:19515853
Cellular Component	GO:0035869	ciliary transition zone	Mks1	IMP		Mouse	MGI:MGI:5288576|PMID:21725307
Cellular Component	GO:0035869	ciliary transition zone	Mks1	IDA		Mouse	PMID:24302887
Cellular Component	GO:0005737	cytoplasm	MKS1	IDA		Human	PMID:17185389
Cellular Component	GO:0016020	membrane	Mks1	IDA		Mouse	PMID:22179047
Cellular Component	GO:0036038	MKS complex	Mks1	IDA		Mouse	MGI:MGI:5288576|PMID:21725307
Cellular Component	GO:0036038	MKS complex	Mks1	IDA		Mouse	PMID:22179047
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Mks1	IMP		Mouse	MGI:MGI:4441259|PMID:17185389
Biological Process	GO:0060411	cardiac septum morphogenesis	Mks1	IMP	MGI:MGI:4821832	Mouse	PMID:27340223
Biological Process	GO:0060271	cilium assembly	MKS1	IMP		Human	PMID:19515853
Biological Process	GO:0060271	cilium assembly	Mks1	IMP		Mouse	MGI:MGI:4441259|PMID:17185389
Biological Process	GO:0060271	cilium assembly	Mks1	IMP		Mouse	MGI:MGI:5288576|PMID:21725307
Biological Process	GO:0060271	cilium assembly	Mks1	IMP		Mouse	MGI:MGI:5013991|PMID:21565611
Biological Process	GO:0061009	common bile duct development	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0007368	determination of left/right symmetry	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0007368	determination of left/right symmetry	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0060030	dorsal convergence	mks1	IMP	ZFIN:ZDB-MRPHLNO-080716-2	Zfish	PMID:18327255
Biological Process	GO:1990403	embryonic brain development	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:0042733	embryonic digit morphogenesis	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:0042733	embryonic digit morphogenesis	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0042733	embryonic digit morphogenesis	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0048706	embryonic skeletal system development	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0010669	epithelial structure maintenance	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0010669	epithelial structure maintenance	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:0010669	epithelial structure maintenance	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0060322	head development	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0044458	motile cilium assembly	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0001843	neural tube closure	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:0001843	neural tube closure	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:1905515	non-motile cilium assembly	Mks1	IMP	MGI:MGI:4410614	Mouse	PMID:19776033
Biological Process	GO:1905515	non-motile cilium assembly	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:1905515	non-motile cilium assembly	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:1905515	non-motile cilium assembly	Mks1	IMP		Mouse	PMID:23454480
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Mks1	IMP	MGI:MGI:4433029	Mouse	PMID:23454480
Biological Process	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	Mks1	IMP	MGI:MGI:4887578	Mouse	PMID:21045211
Biological Process	GO:0003271	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	Mks1	IMP	MGI:MGI:4821832	Mouse	PMID:27340223

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern