Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0005524 | ATP binding | MLKL | IDA | Human | PMID:24219132 | |
Molecular Function | GO:0005524 | ATP binding | Mlkl | IDA | Mouse | MGI:MGI:5532892|PMID:24012422 | |
Molecular Function | GO:0005515 | protein binding | MLKL | IPI | UniProtKB:Q9Y572 | Human | PMID:22265413 |
Molecular Function | GO:0005515 | protein binding | MLKL | IPI | UniProtKB:Q9Y572 | Human | PMID:22265414 |
Molecular Function | GO:0005515 | protein binding | MLKL | IPI | UniProtKB:Q9Y572 | Human | PMID:29883609 |
Molecular Function | GO:0005515 | protein binding | Mlkl | IPI | UniProtKB:Q9QZL0 | Mouse | MGI:MGI:5516182|PMID:22265413 |
Molecular Function | GO:0005515 | protein binding | Mlkl | IPI | UniProtKB:Q9QZL0 | Mouse | MGI:MGI:6436434|PMID:27321907 |
Molecular Function | GO:0005515 | protein binding | Mlkl | IPI | UniProtKB:Q9QZL0 | Mouse | MGI:MGI:5796070|PMID:26559832 |
Molecular Function | GO:0005515 | protein binding | Mlkl | IPI | UniProtKB:Q9QZL0|UniProtKB:U5TQE9 | Mouse | MGI:MGI:5796070|PMID:26559832 |
Molecular Function | GO:0019901 | protein kinase binding | Mlkl | IPI | UniProtKB:Q9QZL0 | Mouse | MGI:MGI:5532892|PMID:24012422 |
Molecular Function | GO:0019901 | protein kinase binding | Mlkl | IPI | UniProtKB:Q9QZL0 | Mouse | MGI:MGI:5532864|PMID:24095729 |
Molecular Function | GO:0044877 | protein-containing complex binding | MLKL | IDA | Human | PMID:22265414 | |
Cellular Component | GO:0030054 | cell junction | MLKL | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005737 | cytoplasm | MLKL | IDA | Human | PMID:24316671 | |
Cellular Component | GO:0005737 | cytoplasm | Mlkl | IDA | Mouse | MGI:MGI:6434626|PMID:32296175 | |
Cellular Component | GO:0005737 | cytoplasm | Mlkl | IDA | Mouse | MGI:MGI:6436412|PMID:32200799 | |
Cellular Component | GO:0005829 | cytosol | MLKL | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005634 | nucleus | Mlkl | IDA | Mouse | MGI:MGI:6436412|PMID:32200799 | |
Cellular Component | GO:0005634 | nucleus | Mlkl | IDA | Mouse | MGI:MGI:6434626|PMID:32296175 | |
Cellular Component | GO:0005886 | plasma membrane | MLKL | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005886 | plasma membrane | MLKL | IDA | Human | PMID:24316671 | |
Cellular Component | GO:0005886 | plasma membrane | MLKL | IDA | Human | PMID:29883610 | |
Cellular Component | GO:0005886 | plasma membrane | Mlkl | IDA | Mouse | MGI:MGI:6436412|PMID:32200799 | |
Biological Process | GO:0051607 | defense response to virus | Mlkl | IDA | Mouse | MGI:MGI:6434626|PMID:32296175 | |
Biological Process | GO:0051607 | defense response to virus | Mlkl | IMP | Mouse | MGI:MGI:6436434|PMID:27321907 | |
Biological Process | GO:0051607 | defense response to virus | Mlkl | IDA | Mouse | MGI:MGI:6436412|PMID:32200799 | |
Biological Process | GO:0097528 | execution phase of necroptosis | Mlkl | IDA | Mouse | MGI:MGI:6434626|PMID:32296175 | |
Biological Process | GO:0097528 | execution phase of necroptosis | Mlkl | IDA | Mouse | MGI:MGI:6436412|PMID:32200799 | |
Biological Process | GO:0097528 | execution phase of necroptosis | Mlkl | IMP | Mouse | MGI:MGI:6436434|PMID:27321907 | |
Biological Process | GO:0070266 | necroptotic process | MLKL | IMP | Human | PMID:22265414 | |
Biological Process | GO:0070266 | necroptotic process | MLKL | IMP | Human | PMID:24316671 | |
Biological Process | GO:0070266 | necroptotic process | MLKL | IMP | Human | PMID:29883610 | |
Biological Process | GO:0070266 | necroptotic process | Mlkl | IMP | Mouse | MGI:MGI:5532894|PMID:23835476 | |
Biological Process | GO:0070266 | necroptotic process | Mlkl | IMP | Mouse | MGI:MGI:5532892|PMID:24012422 | |
Biological Process | GO:0097527 | necroptotic signaling pathway | MLKL | IMP | Human | PMID:22265413 | |
Biological Process | GO:0097527 | necroptotic signaling pathway | Mlkl | IMP | Mouse | MGI:MGI:5516182|PMID:22265413 | |
Biological Process | GO:0070207 | protein homotrimerization | MLKL | IDA | Human | PMID:24316671 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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