Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mlxipl

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MLXIPL
- Mouse genes Mlxipl
- Rat genes Mlxipl
- Zfish genes mlxip
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mlxipl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Mlxipl	IDA		Mouse	MGI:MGI:1931895\|PMID:11230181
Molecular Function	GO:0003677	DNA binding	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Molecular Function	GO:0001216	DNA-binding transcription activator activity	MLXIPL	IDA		Human	PMID:21084751
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mlxipl	IDA		Mouse	PMID:21084751
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mlxipl	IMP		Mouse	PMID:15496471
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Mlxipl	IGI	MGI:MGI:1339639	Mouse	PMID:21471514
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Mlxipl	IDA		Mouse	PMID:18606808
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MLXIPL	IDA		Human	PMID:21084751
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Mlxipl	IDA		Mouse	MGI:MGI:1931895\|PMID:11230181
Molecular Function	GO:0005515	protein binding	Mlxipl	IPI	UniProtKB:Q6P069	Mouse	MGI:MGI:5487506\|PMID:22338092
Molecular Function	GO:0005515	protein binding	Mlxipl	IPI	UniProtKB:Q9GZT8	Mouse	MGI:MGI:3777523\|PMID:15163635
Molecular Function	GO:0005515	protein binding	Mlxipl	IPI	UniProtKB:P31946	Rat	PMID:20025850\|RGD:8554541
Molecular Function	GO:0005515	protein binding	Mlxipl	IPI	UniProtKB:Q80U96	Rat	PMID:20025850\|RGD:8554541
Molecular Function	GO:0046982	protein heterodimerization activity	MLXIPL	IPI	UniProtKB:Q9UH92	Human	PMID:11230181
Molecular Function	GO:0019901	protein kinase binding	Mlxipl	IPI	UniProtKB:P54645	Rat	PMID:11724780\|RGD:634534
Molecular Function	GO:0019901	protein kinase binding	Mlxipl	IPI	UniProtKB:Q09137	Rat	PMID:11724780\|RGD:634534
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mlxipl	IDA		Mouse	MGI:MGI:1931895\|PMID:11230181
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MLXIPL	IPI	UniProtKB:Q9UH92	Human	PMID:11230181
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Mlxipl	IDA		Mouse	MGI:MGI:1931895\|PMID:11230181
Molecular Function	GO:0043565	sequence-specific DNA binding	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Cellular Component	GO:0000785	chromatin	MLXIPL	IDA		Human	PMID:21084751
Cellular Component	GO:0005737	cytoplasm	Mlxipl	IDA		Mouse	MGI:MGI:3777523\|PMID:15163635
Cellular Component	GO:0005737	cytoplasm	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Cellular Component	GO:0005829	cytosol	MLXIPL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Mlxipl	IDA		Rat	PMID:20025850\|RGD:8554541
Cellular Component	GO:0005654	nucleoplasm	MLXIPL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Mlxipl	IDA		Mouse	PMID:18606808
Cellular Component	GO:0005634	nucleus	Mlxipl	IDA		Mouse	MGI:MGI:3777523\|PMID:15163635
Cellular Component	GO:0005634	nucleus	Mlxipl	IDA		Mouse	PMID:21084751
Cellular Component	GO:0005634	nucleus	Mlxipl	IMP		Mouse	PMID:15496471
Cellular Component	GO:0005634	nucleus	Mlxipl	IDA		Mouse	PMID:21471514
Cellular Component	GO:0005634	nucleus	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Cellular Component	GO:0005634	nucleus	Mlxipl	IDA		Rat	PMID:20025850\|RGD:8554541
Cellular Component	GO:0005667	transcription regulator complex	Mlxipl	IDA		Mouse	PMID:11230181
Biological Process	GO:0071333	cellular response to glucose stimulus	Mlxipl	IDA		Rat	PMID:20025850\|RGD:8554541
Biological Process	GO:0097009	energy homeostasis	Mlxipl	IMP		Rat	PMID:11724780\|RGD:634534
Biological Process	GO:0055089	fatty acid homeostasis	Mlxipl	IMP		Rat	PMID:11724780\|RGD:634534
Biological Process	GO:0042593	glucose homeostasis	Mlxipl	IMP		Mouse	MGI:MGI:3041761\|PMID:15118080
Biological Process	GO:0010255	glucose mediated signaling pathway	Mlxipl	IDA		Mouse	MGI:MGI:4457241\|PMID:18591247
Biological Process	GO:0008610	lipid biosynthetic process	MLXIPL	IDA		Human	PMID:21084751
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mlxipl	IDA		Mouse	MGI:MGI:1931895\|PMID:11230181
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	MLXIPL	IMP		Human	PMID:19995986
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	MLXIPL	IMP		Human	PMID:19995986
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mlxipl	IDA		Mouse	PMID:11230181
Biological Process	GO:0008284	positive regulation of cell population proliferation	MLXIPL	IMP		Human	PMID:19995986
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mlxipl	IDA		Mouse	MGI:MGI:3777523\|PMID:15163635
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	Mlxipl	IMP		Mouse	MGI:MGI:3041761\|PMID:15118080
Biological Process	GO:0045821	positive regulation of glycolytic process	MLXIPL	IMP		Human	PMID:19995986
Biological Process	GO:0045821	positive regulation of glycolytic process	Mlxipl	IMP		Mouse	MGI:MGI:3041761\|PMID:15118080
Biological Process	GO:0045821	positive regulation of glycolytic process	Mlxipl	IDA		Mouse	PMID:14742444
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	MLXIPL	IMP		Human	PMID:19995986
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Mlxipl	IMP		Mouse	PMID:15496471
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Mlxipl	IGI	MGI:MGI:1339639	Mouse	PMID:21471514
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mlxipl	IMP		Mouse	MGI:MGI:3041761\|PMID:15118080
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mlxipl	IDA		Mouse	PMID:18606808
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	Mlxipl	IDA		Mouse	PMID:14742444
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	Mlxipl	IMP		Mouse	PMID:15496471
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	Mlxipl	IGI	MGI:MGI:1339639	Mouse	PMID:21471514
Biological Process	GO:0006110	regulation of glycolytic process	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Mlxipl	IDA		Rat	PMID:11724780\|RGD:634534
Biological Process	GO:0009749	response to glucose	Mlxipl	IDA		Rat	PMID:11470916\|RGD:1580598
Biological Process	GO:0031667	response to nutrient levels	Mlxipl	IEP		Rat	PMID:25943649\|RGD:152995488

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.