Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MLYCD
  • Mouse genes Mlycd
  • Rat genes Mlycd
  • Zfish genes mlycd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mlycd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	MLYCD	IPI	UniProtKB:O95822	Human	PMID:23791943
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	MLYCD	IDA		Human	PMID:10417274
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	MLYCD	IDA		Human	PMID:10455107
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	MLYCD	IDA		Human	PMID:15003260
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	MLYCD	IDA		Human	PMID:9869665
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	Mlycd	IDA		Mouse	MGI:MGI:5501374|PMID:23746352
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	Mlycd	IDA		Rat	PMID:12065578|RGD:631891
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Molecular Function	GO:0050080	malonyl-CoA decarboxylase activity	Mlycd	IDA		Rat	PMID:17316539|RGD:1600790
Molecular Function	GO:0005515	protein binding	Mlycd	IPI	UniProtKB:Q8R216	Mouse	MGI:MGI:5501374|PMID:23746352
Cellular Component	GO:0005737	cytoplasm	MLYCD	IDA		Human	PMID:10455107
Cellular Component	GO:0005737	cytoplasm	Mlycd	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005737	cytoplasm	Mlycd	IDA		Rat	PMID:10455107|RGD:1600798
Cellular Component	GO:0005737	cytoplasm	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Cellular Component	GO:0005829	cytosol	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Cellular Component	GO:0005759	mitochondrial matrix	Mlycd	IDA		Mouse	MGI:MGI:5501374|PMID:23746352
Cellular Component	GO:0005759	mitochondrial matrix	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Cellular Component	GO:0005739	mitochondrion	MLYCD	IDA		Human	PMID:10417274
Cellular Component	GO:0005739	mitochondrion	Mlycd	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	Mlycd	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Mlycd	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Cellular Component	GO:0005782	peroxisomal matrix	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Cellular Component	GO:0005777	peroxisome	MLYCD	IDA		Human	PMID:10417274
Cellular Component	GO:0005777	peroxisome	MLYCD	IDA		Human	PMID:10455107
Cellular Component	GO:0005777	peroxisome	Mlycd	IDA		Rat	PMID:10455107|RGD:1600798
Cellular Component	GO:0005777	peroxisome	Mlycd	IDA		Rat	PMID:16298369|RGD:1600793
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	MLYCD	IDA		Human	PMID:10417274
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	MLYCD	IDA		Human	PMID:10455107
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	MLYCD	IDA		Human	PMID:9869665
Biological Process	GO:0006085	acetyl-CoA biosynthetic process	Mlycd	IDA		Rat	PMID:17316539|RGD:1600790
Biological Process	GO:0006633	fatty acid biosynthetic process	MLYCD	IDA		Human	PMID:15003260
Biological Process	GO:0006633	fatty acid biosynthetic process	Mlycd	IMP		Rat	PMID:15105298|RGD:1600796
Biological Process	GO:0019395	fatty acid oxidation	Mlycd	IDA		Rat	PMID:17316539|RGD:1600790
Biological Process	GO:2001294	malonyl-CoA catabolic process	MLYCD	IDA		Human	PMID:10417274
Biological Process	GO:2001294	malonyl-CoA catabolic process	MLYCD	IDA		Human	PMID:10455107
Biological Process	GO:2001294	malonyl-CoA catabolic process	MLYCD	IDA		Human	PMID:15003260
Biological Process	GO:2001294	malonyl-CoA catabolic process	Mlycd	IDA		Mouse	MGI:MGI:5501374|PMID:23746352
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	MLYCD	IMP		Human	PMID:18314420
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	Mlycd	IDA		Mouse	MGI:MGI:5501374|PMID:23746352
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Mlycd	IDA		Rat	PMID:10516138|RGD:1600797
Biological Process	GO:0046320	regulation of fatty acid oxidation	Mlycd	IMP		Rat	PMID:15105298|RGD:1600796
Biological Process	GO:0010906	regulation of glucose metabolic process	MLYCD	IMP		Human	PMID:18314420
Biological Process	GO:0010906	regulation of glucose metabolic process	Mlycd	IMP		Rat	PMID:15105298|RGD:1600796
Biological Process	GO:0002931	response to ischemia	Mlycd	IMP		Rat	PMID:15105298|RGD:1600796

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern