Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MME
  • Mouse genes Mme
  • Rat genes Mme
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mme

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1901612	cardiolipin binding	MME	IDA		Human	PMID:22183801
Molecular Function	GO:0004175	endopeptidase activity	MME	IGI	UniProtKB:Q61391	Human	PMID:14749444
Molecular Function	GO:0004175	endopeptidase activity	MME	IDA		Human	PMID:15100223
Molecular Function	GO:0004175	endopeptidase activity	MME	IDA		Human	PMID:15283675
Molecular Function	GO:0004175	endopeptidase activity	MME	IDA		Human	PMID:18539150
Molecular Function	GO:0004175	endopeptidase activity	MME	IMP		Human	PMID:19057576
Molecular Function	GO:0004175	endopeptidase activity	MME	IDA		Human	PMID:20876573
Molecular Function	GO:0004175	endopeptidase activity	MME	IMP		Human	PMID:24825898
Molecular Function	GO:0004175	endopeptidase activity	MME	IMP		Human	PMID:2531377
Molecular Function	GO:0004175	endopeptidase activity	MME	IDA		Human	PMID:8168535
Molecular Function	GO:0008238	exopeptidase activity	MME	IDA		Human	PMID:6208535
Molecular Function	GO:0004222	metalloendopeptidase activity	MME	IDA		Human	PMID:15283675
Molecular Function	GO:0004222	metalloendopeptidase activity	MME	IMP		Human	PMID:2521388
Molecular Function	GO:0004222	metalloendopeptidase activity	MME	IDA		Human	PMID:27588448
Molecular Function	GO:0004222	metalloendopeptidase activity	MME	IDA		Human	PMID:6208535
Molecular Function	GO:0004222	metalloendopeptidase activity	MME	IDA		Human	PMID:6349683
Molecular Function	GO:0070012	oligopeptidase activity	Mme	IDA		Rat	PMID:3522576|RGD:13801015
Molecular Function	GO:0008233	peptidase activity	Mme	IDA		Mouse	PMID:15944124
Molecular Function	GO:0042277	peptide binding	Mme	IDA		Rat	PMID:15308303|RGD:1600807
Molecular Function	GO:0001786	phosphatidylserine binding	MME	IDA		Human	PMID:22183801
Molecular Function	GO:0005515	protein binding	MME	IPI	UniProtKB:P04792	Human	PMID:17342744
Molecular Function	GO:0005515	protein binding	MME	IPI	UniProtKB:P21926	Human	PMID:23289620
Molecular Function	GO:0005515	protein binding	MME	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MME	IPI	UniProtKB:Q06787-7	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	MME	IDA		Human	PMID:22183801
Molecular Function	GO:0008270	zinc ion binding	MME	IDA		Human	PMID:8168535
Cellular Component	GO:0030424	axon	MME	IGI	UniProtKB:Q61391	Human	PMID:14749444
Cellular Component	GO:0030424	axon	Mme	IDA		Mouse	PMID:12074840
Cellular Component	GO:0005903	brush border	MME	IDA		Human	PMID:22272689
Cellular Component	GO:0005737	cytoplasm	MME	IDA		Human	PMID:20876573
Cellular Component	GO:0005737	cytoplasm	MME	IDA		Human	PMID:22272689
Cellular Component	GO:0031410	cytoplasmic vesicle	MME	IDA		Human	PMID:15100223
Cellular Component	GO:0030425	dendrite	Mme	IDA		Mouse	PMID:12074840
Cellular Component	GO:0005769	early endosome	MME	IDA		Human	PMID:15100223
Cellular Component	GO:0070062	extracellular exosome	MME	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MME	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	MME	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	Mme	IDA		Mouse	PMID:15944124
Cellular Component	GO:0016020	membrane	Mme	IDA		Rat	PMID:15308303|RGD:1600807
Cellular Component	GO:0045121	membrane raft	MME	IDA		Human	PMID:15100223
Cellular Component	GO:0045121	membrane raft	MME	IDA		Human	PMID:22183801
Cellular Component	GO:0044306	neuron projection terminus	Mme	IDA		Mouse	PMID:12074840
Cellular Component	GO:0043025	neuronal cell body	MME	IDA		Human	PMID:15100223
Cellular Component	GO:0043025	neuronal cell body	MME	IGI	UniProtKB:P05067	Human	PMID:24825898
Cellular Component	GO:0005886	plasma membrane	MME	IDA		Human	PMID:20876573
Cellular Component	GO:0005886	plasma membrane	MME	IDA		Human	PMID:22272689
Cellular Component	GO:0005886	plasma membrane	Mme	IDA		Rat	PMID:15908023|RGD:1581744
Cellular Component	GO:0098793	presynapse	MME	IGI	UniProtKB:Q61391	Human	PMID:14749444
Cellular Component	GO:0045202	synapse	Mme	IDA		Mouse	PMID:12074840
Cellular Component	GO:0008021	synaptic vesicle	Mme	IDA		Mouse	PMID:12074840
Cellular Component	GO:0005802	trans-Golgi network	MME	IDA		Human	PMID:15100223
Biological Process	GO:0007568	aging	MME	IEP		Human	PMID:16226260
Biological Process	GO:0097242	amyloid-beta clearance	MME	IDA		Human	PMID:12657655
Biological Process	GO:0097242	amyloid-beta clearance	MME	IGI	UniProtKB:Q61391	Human	PMID:14749444
Biological Process	GO:0097242	amyloid-beta clearance	MME	IDA		Human	PMID:15100223
Biological Process	GO:0097242	amyloid-beta clearance	Mme	IGI	UniProtKB:P05067	Mouse	MGI:MGI:3689460|PMID:16636059
Biological Process	GO:0097242	amyloid-beta clearance	Mme	IDA		Rat	PMID:19406747|RGD:13210538
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	MME	IDA		Human	PMID:15100223
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	MME	IGI	UniProtKB:P05067	Human	PMID:24825898
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	Mme	IMP		Rat	PMID:18941241|RGD:13825436
Biological Process	GO:0050435	amyloid-beta metabolic process	Mme	IDA		Mouse	PMID:12074840
Biological Process	GO:0010815	bradykinin catabolic process	MME	IDA		Human	PMID:6349683
Biological Process	GO:0071345	cellular response to cytokine stimulus	MME	IDA		Human	PMID:20876573
Biological Process	GO:0071492	cellular response to UV-A	MME	IDA		Human	PMID:20876573
Biological Process	GO:0071493	cellular response to UV-B	MME	IDA		Human	PMID:20876573
Biological Process	GO:0046449	creatinine metabolic process	MME	IMP		Human	PMID:22024547
Biological Process	GO:0042447	hormone catabolic process	MME	IDA		Human	PMID:6349683
Biological Process	GO:0001822	kidney development	MME	IEP		Human	PMID:22272689
Biological Process	GO:0001822	kidney development	Mme	IEP		Rat	PMID:1547865|RGD:13801036
Biological Process	GO:0007611	learning or memory	MME	IGI	UniProtKB:P05067	Human	PMID:24825898
Biological Process	GO:0030324	lung development	Mme	IEP		Rat	PMID:1547865|RGD:13801036
Biological Process	GO:0061837	neuropeptide processing	MME	IGI	UniProtKB:P05067	Human	PMID:24825898
Biological Process	GO:0006518	peptide metabolic process	Mme	IMP		Rat	PMID:10642323|RGD:1581953
Biological Process	GO:0001890	placenta development	Mme	IEP		Rat	PMID:1547865|RGD:13801036
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Mme	IGI	UniProtKB:P05067	Mouse	MGI:MGI:3689460|PMID:16636059
Biological Process	GO:0050769	positive regulation of neurogenesis	MME	IGI	UniProtKB:P05067	Human	PMID:24825898
Biological Process	GO:0030163	protein catabolic process	Mme	IDA		Rat	PMID:15308303|RGD:1600807
Biological Process	GO:0030163	protein catabolic process	Mme	IDA		Rat	PMID:15908023|RGD:1581744
Biological Process	GO:0006508	proteolysis	MME	IGI	UniProtKB:Q61391	Human	PMID:14749444
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:15100223
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:18539150
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:18602473
Biological Process	GO:0006508	proteolysis	MME	IMP		Human	PMID:19057576
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:20876573
Biological Process	GO:0006508	proteolysis	MME	IMP		Human	PMID:24825898
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:27588448
Biological Process	GO:0006508	proteolysis	MME	IDA		Human	PMID:8168535
Biological Process	GO:0090399	replicative senescence	MME	IEP		Human	PMID:20876573
Biological Process	GO:0043627	response to estrogen	Mme	IDA		Rat	PMID:15308303|RGD:1600807
Biological Process	GO:0019233	sensory perception of pain	Mme	IMP		Mouse	MGI:MGI:5315379|PMID:9751784
Biological Process	GO:0010814	substance P catabolic process	MME	IDA		Human	PMID:6208535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern