Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMP1
  • Mouse genes Mmp1a
  • Rat genes Mmp1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmp1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	MMP1	IDA		Human	PMID:19022250
Molecular Function	GO:0004222	metalloendopeptidase activity	MMP1	IDA		Human	PMID:9920899
Molecular Function	GO:0008233	peptidase activity	MMP1	IDA		Human	PMID:23845380
Molecular Function	GO:0008233	peptidase activity	Mmp1a	IDA		Mouse	PMID:11113146
Molecular Function	GO:0008233	peptidase activity	Mmp1	IDA		Rat	PMID:8531210|RGD:7207198
Molecular Function	GO:0005515	protein binding	Mmp1	IPI	RGD:621675	Rat	PMID:21846328|RGD:7207284
Cellular Component	GO:0005737	cytoplasm	Mmp1	IDA		Rat	PMID:9732233|RGD:7207196
Cellular Component	GO:0005615	extracellular space	Mmp1	IDA		Rat	PMID:22410640|RGD:7207278
Biological Process	GO:0071312	cellular response to alkaloid	Mmp1	IEP		Rat	PMID:21108488|RGD:7207365
Biological Process	GO:0071498	cellular response to fluid shear stress	Mmp1	IEP		Rat	PMID:19880665|RGD:7207384
Biological Process	GO:0071347	cellular response to interleukin-1	Mmp1	IEP		Rat	PMID:22410640|RGD:7207278
Biological Process	GO:0071283	cellular response to iron(III) ion	Mmp1	IEP		Rat	PMID:21683124|RGD:7207286
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Mmp1	IEP		Rat	PMID:21683124|RGD:7207286
Biological Process	GO:0071407	cellular response to organic cyclic compound	Mmp1	IEP		Rat	PMID:21811993|RGD:7207285
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	Mmp1	IEP		Rat	PMID:20564215|RGD:7207371
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Mmp1	IEP		Rat	PMID:22410640|RGD:7207278
Biological Process	GO:0071492	cellular response to UV-A	MMP1	IDA		Human	PMID:31380578
Biological Process	GO:0071305	cellular response to vitamin D	Mmp1	IEP		Rat	PMID:22064970|RGD:7207281
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Mmp1	IEP		Rat	PMID:19847888|RGD:7207385
Biological Process	GO:0001553	luteinization	Mmp1	IEP		Rat	PMID:8835383|RGD:7207087
Biological Process	GO:0001554	luteolysis	Mmp1	IEP		Rat	PMID:8835383|RGD:7207087
Biological Process	GO:0010763	positive regulation of fibroblast migration	Mmp1	IMP		Rat	PMID:19465549|RGD:7207389
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	MMP1	IDA		Human	PMID:19022250
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Mmp1	IMP		Rat	PMID:19465549|RGD:7207389
Biological Process	GO:0006508	proteolysis	MMP1	IDA		Human	PMID:15863497
Biological Process	GO:0006508	proteolysis	MMP1	IDA		Human	PMID:19022250
Biological Process	GO:0014854	response to inactivity	Mmp1	IEP		Rat	PMID:20826544|RGD:5147848
Biological Process	GO:0071680	response to indole-3-methanol	Mmp1	IEP		Rat	PMID:20880187|RGD:7207367
Biological Process	GO:0009612	response to mechanical stimulus	Mmp1	IEP		Rat	PMID:21488874|RGD:7207360
Biological Process	GO:0009410	response to xenobiotic stimulus	Mmp1	IEP		Rat	PMID:23325540|RGD:7207215

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern