Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMP3
  • Mouse genes Mmp3
  • Rat genes Mmp3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	MMP3	IDA		Human	PMID:15863497
Molecular Function	GO:0004175	endopeptidase activity	MMP3	IDA		Human	PMID:19022250
Molecular Function	GO:0004175	endopeptidase activity	MMP3	IDA		Human	PMID:20969476
Molecular Function	GO:0008237	metallopeptidase activity	MMP3	IDA		Human	PMID:9573338
Molecular Function	GO:0008233	peptidase activity	MMP3	IDA		Human	PMID:23845380
Molecular Function	GO:0005515	protein binding	MMP3	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MMP3	IPI	UniProtKB:P16035	Human	PMID:9573338
Molecular Function	GO:0044877	protein-containing complex binding	Mmp3	IDA		Rat	PMID:16935996|RGD:2325938
Cellular Component	GO:0044297	cell body	Mmp3	IDA		Rat	PMID:18629001|RGD:2325874
Cellular Component	GO:0005829	cytosol	Mmp3	IDA		Mouse	MGI:MGI:5575467|PMID:20969476
Cellular Component	GO:0030425	dendrite	Mmp3	IDA		Rat	PMID:18629001|RGD:2325874
Cellular Component	GO:0005615	extracellular space	Mmp3	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Mmp3	IDA		Rat	PMID:18439420|RGD:2325876
Cellular Component	GO:0005739	mitochondrion	Mmp3	IDA		Mouse	MGI:MGI:5575467|PMID:20969476
Cellular Component	GO:0005634	nucleus	Mmp3	IDA		Rat	PMID:18629001|RGD:2325874
Cellular Component	GO:0032991	protein-containing complex	Mmp3	IDA		Rat	PMID:16935996|RGD:2325938
Biological Process	GO:0071230	cellular response to amino acid stimulus	Mmp3	IDA		Mouse	PMID:20548288
Biological Process	GO:0071460	cellular response to cell-matrix adhesion	Mmp3	IEP		Rat	PMID:12963432|RGD:2325968
Biological Process	GO:0071347	cellular response to interleukin-1	Mmp3	IEP		Rat	PMID:16046515|RGD:2313720
Biological Process	GO:0071492	cellular response to UV-A	MMP3	IDA		Human	PMID:31380578
Biological Process	GO:0007565	female pregnancy	Mmp3	IEP		Rat	PMID:15672041|RGD:2325960
Biological Process	GO:0010727	negative regulation of hydrogen peroxide metabolic process	MMP3	IDA		Human	PMID:20969476
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Mmp3	IMP		Mouse	MGI:MGI:5575467|PMID:20969476
Biological Process	GO:0030335	positive regulation of cell migration	Mmp3	IMP		Rat	PMID:23142217|RGD:8694107
Biological Process	GO:1903209	positive regulation of oxidative stress-induced cell death	Mmp3	IMP		Mouse	MGI:MGI:5575467|PMID:20969476
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	MMP3	IDA		Human	PMID:19022250
Biological Process	GO:0030163	protein catabolic process	Mmp3	IMP		Mouse	MGI:MGI:5575467|PMID:20969476
Biological Process	GO:0006508	proteolysis	MMP3	IDA		Human	PMID:12867428
Biological Process	GO:0006508	proteolysis	MMP3	IDA		Human	PMID:15863497
Biological Process	GO:0006508	proteolysis	MMP3	IDA		Human	PMID:19022250
Biological Process	GO:0006508	proteolysis	MMP3	IDA		Human	PMID:20969476
Biological Process	GO:0006508	proteolysis	Mmp3	IMP		Mouse	MGI:MGI:5575467|PMID:20969476
Biological Process	GO:0030334	regulation of cell migration	Mmp3	IMP		Mouse	PMID:11869290
Biological Process	GO:0043200	response to amino acid	Mmp3	IEP		Rat	PMID:17083784|RGD:2290426
Biological Process	GO:0034097	response to cytokine	Mmp3	IEP		Rat	PMID:10435007|RGD:2290469
Biological Process	GO:0032355	response to estradiol	Mmp3	IEP		Rat	PMID:19889233|RGD:2325866
Biological Process	GO:0001666	response to hypoxia	Mmp3	IEP		Rat	PMID:15099024|RGD:2325962
Biological Process	GO:0070555	response to interleukin-1	Mmp3	IEP		Rat	PMID:16290189|RGD:2325943
Biological Process	GO:0032496	response to lipopolysaccharide	Mmp3	IEP		Rat	PMID:19345799|RGD:2325870
Biological Process	GO:0009612	response to mechanical stimulus	Mmp3	IEP		Rat	PMID:16140193|RGD:2325955
Biological Process	GO:0034612	response to tumor necrosis factor	Mmp3	IEP		Rat	PMID:17704356|RGD:2325928
Biological Process	GO:0042060	wound healing	Mmp3	IEP		Rat	PMID:19834065|RGD:2325869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern