Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MNT
  • Mouse genes Mnt
  • Rat genes Mnt
  • Zfish genes mnta,mntb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mnt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Mnt	IDA		Mouse	PMID:16103876
Molecular Function	GO:0003677	DNA binding	Mnt	IDA		Mouse	PMID:12970171
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mnt	IMP		Mouse	PMID:16103876
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mnt	IMP	MGI:MGI:2678322	Mouse	PMID:12970171
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MNT	IDA		Human	PMID:9184233
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MNT	IMP		Human	PMID:9598315
Molecular Function	GO:0005515	protein binding	MNT	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mnt	IPI	PR:Q62141	Mouse	PMID:16103876
Molecular Function	GO:0005515	protein binding	Mnt	IPI	PR:O09106	Mouse	PMID:16103876
Molecular Function	GO:0005515	protein binding	Mnt	IPI	PR:Q60520	Mouse	PMID:16103876
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MNT	IDA		Human	PMID:9184233
Cellular Component	GO:0005654	nucleoplasm	MNT	IDA		Human	GO_REF:0000052
Biological Process	GO:0090398	cellular senescence	Mnt	IMP	MGI:MGI:2678322	Mouse	PMID:12970171
Biological Process	GO:0006351	DNA-templated transcription	Mnt	IMP	MGI:MGI:2678322	Mouse	MGI:MGI:2675510|PMID:12970171
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Mnt	IMP	MGI:MGI:2678322	Mouse	PMID:12970171
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MNT	IDA		Human	PMID:9184233
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MNT	IMP		Human	PMID:9598315
Biological Process	GO:0051726	regulation of cell cycle	Mnt	IMP	MGI:MGI:2678322	Mouse	PMID:12970171
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mnt	IMP		Mouse	PMID:16103876
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mnt	IMP	MGI:MGI:2678322	Mouse	PMID:12970171

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern