Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MNX1
  • Mouse genes Mnx1
  • Rat genes Mnx1
  • Zfish genes mnx1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mnx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Mnx1	IDA		Rat	PMID:18539116|RGD:155230693
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MNX1	IDA		Human	PMID:28473536
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	Mnx1	IDA		Rat	PMID:18539116|RGD:155230693
Cellular Component	GO:0000785	chromatin	Mnx1	IDA		Mouse	MGI:MGI:7339313|PMID:18539116
Cellular Component	GO:0005829	cytosol	MNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	MNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mnx1	IDA		Mouse	PMID:17042795
Cellular Component	GO:0005634	nucleus	Mnx1	IDA		Mouse	PMID:23610558
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0021953	central nervous system neuron differentiation	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0021953	central nervous system neuron differentiation	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0021953	central nervous system neuron differentiation	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0060539	diaphragm development	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0060539	diaphragm development	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0060539	diaphragm development	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Mnx1	IDA		Mouse	PMID:18590716
Biological Process	GO:0031018	endocrine pancreas development	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10471501
Biological Process	GO:0031018	endocrine pancreas development	mnx1	IGI	ZFIN:ZDB-MRPHLNO-080814-1,ZFIN:ZDB-MRPHLNO-111028-2	Zfish	PMID:22034951
Biological Process	GO:0008045	motor neuron axon guidance	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0008045	motor neuron axon guidance	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0008045	motor neuron axon guidance	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mnx1	IDA		Mouse	MGI:MGI:7339313|PMID:18539116
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mnx1	IDA		Rat	PMID:18539116|RGD:155230693
Biological Process	GO:0021675	nerve development	Mnx1	IMP	MGI:MGI:2447793	Mouse	PMID:11395002
Biological Process	GO:0030182	neuron differentiation	Mnx1	IMP	MGI:MGI:2447793	Mouse	PMID:11395002
Biological Process	GO:0001764	neuron migration	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0001764	neuron migration	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0001764	neuron migration	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0048812	neuron projection morphogenesis	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0048812	neuron projection morphogenesis	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0048812	neuron projection morphogenesis	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0031016	pancreas development	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10471501
Biological Process	GO:0009791	post-embryonic development	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0009791	post-embryonic development	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0009791	post-embryonic development	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0060541	respiratory system development	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0060541	respiratory system development	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0060541	respiratory system development	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Mnx1	IMP		Mouse	MGI:MGI:7339313|PMID:18539116
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Mnx1	IMP	MGI:MGI:2182363	Mouse	PMID:10482234
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Mnx1	IMP	MGI:MGI:2182358	Mouse	PMID:10482234
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	Mnx1	IMP	MGI:MGI:2182361	Mouse	PMID:10482234
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	mnx1	IGI	ZFIN:ZDB-MRPHLNO-130401-1,ZFIN:ZDB-MRPHLNO-130401-2,ZFIN:ZDB-MRPHLNO-130403-1	Zfish	PMID:23122226
Biological Process	GO:0003309	type B pancreatic cell differentiation	mnx1	IMP	ZFIN:ZDB-MRPHLNO-111028-2	Zfish	PMID:21989909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern