Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MPO
  • Mouse genes Mpo
  • Rat genes Mpo
  • Zfish genes mpx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mpo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	MPO	IDA		Human	PMID:11907569
Molecular Function	GO:0004601	peroxidase activity	MPO	IDA		Human	PMID:10772654
Molecular Function	GO:0004601	peroxidase activity	MPO	IDA		Human	PMID:11907569
Molecular Function	GO:0004601	peroxidase activity	MPO	IDA		Human	PMID:24035742
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Mouse	PMID:11980719
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Mouse	PMID:10085024
Molecular Function	GO:0004601	peroxidase activity	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Mouse	PMID:15159534
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Mouse	PMID:11792727
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Rat	PMID:12922978|RGD:1302251
Molecular Function	GO:0004601	peroxidase activity	Mpo	IDA		Rat	PMID:17363466|RGD:1625357
Molecular Function	GO:0004601	peroxidase activity	mpx	IDA		Zfish	PMID:22940471
Molecular Function	GO:0005515	protein binding	MPO	IPI	UniProtKB:P27918	Human	PMID:24355864
Molecular Function	GO:0005515	protein binding	MPO	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Cellular Component	GO:0042582	azurophil granule	MPO	IDA		Human	PMID:2981589
Cellular Component	GO:0005737	cytoplasm	mpx	IDA		Zfish	PMID:19097072
Cellular Component	GO:0005737	cytoplasm	mpx	IDA		Zfish	PMID:11698295
Cellular Component	GO:0070062	extracellular exosome	MPO	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MPO	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MPO	IDA		Human	PMID:10772654
Cellular Component	GO:0005615	extracellular space	MPO	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	MPO	IDA		Human	PMID:25645918
Cellular Component	GO:0005615	extracellular space	Mpo	IDA		Rat	PMID:7996547|RGD:2317975
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Mpo	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005654	nucleoplasm	MPO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MPO	HDA		Human	PMID:21630459
Cellular Component	GO:0030141	secretory granule	MPO	IDA		Human	PMID:11907569
Biological Process	GO:0007568	aging	Mpo	IEP		Rat	PMID:15788232|RGD:2317972
Biological Process	GO:0050832	defense response to fungus	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Biological Process	GO:0042744	hydrogen peroxide catabolic process	MPO	IDA		Human	PMID:11907569
Biological Process	GO:0042744	hydrogen peroxide catabolic process	MPO	IDA		Human	PMID:10772654
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Mpo	IDA		Mouse	PMID:10085024
Biological Process	GO:0002149	hypochlorous acid biosynthetic process	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Biological Process	GO:0006954	inflammatory response	mpx	IMP	ZFIN:ZDB-GENO-150702-1	Zfish	PMID:25665803
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	MPO	IDA		Human	PMID:10772654
Biological Process	GO:0010310	regulation of hydrogen peroxide metabolic process	mpx	IMP	ZFIN:ZDB-GENO-121213-40	Zfish	PMID:22940471
Biological Process	GO:0019430	removal of superoxide radicals	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Biological Process	GO:0002679	respiratory burst involved in defense response	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024
Biological Process	GO:0009617	response to bacterium	mpx	IDA		Zfish	PMID:17055441
Biological Process	GO:0009617	response to bacterium	mpx	IDA		Zfish	PMID:17804254
Biological Process	GO:0032094	response to food	Mpo	IEP		Rat	PMID:15788232|RGD:2317972
Biological Process	GO:1990268	response to gold nanoparticle	Mpo	IEP		Rat	PMID:23150627|RGD:7815044
Biological Process	GO:0032496	response to lipopolysaccharide	Mpo	IEP		Rat	PMID:15788232|RGD:2317972
Biological Process	GO:0009612	response to mechanical stimulus	Mpo	IEP		Rat	PMID:9518261|RGD:2317974
Biological Process	GO:0006979	response to oxidative stress	Mpo	IDA		Rat	PMID:12922978|RGD:1302251
Biological Process	GO:0001878	response to yeast	Mpo	IMP	MGI:MGI:2176344	Mouse	PMID:10085024

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern