Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MPZ
  • Mouse genes Mpz
  • Rat genes Mpz
  • Zfish genes mpz
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mpz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Mpz	IPI	UniProtKB:Q08460	Mouse	MGI:MGI:3852248|PMID:19423573
Cellular Component	GO:0016323	basolateral plasma membrane	Mpz	IDA		Rat	PMID:16788992|RGD:9685788
Cellular Component	GO:0005764	lysosome	Mpz	IDA		Rat	PMID:16788992|RGD:9685788
Cellular Component	GO:0043209	myelin sheath	mpz	IDA		Zfish	PMID:19126863
Cellular Component	GO:0005886	plasma membrane	MPZ	IDA		Human	PMID:18337304
Cellular Component	GO:0005886	plasma membrane	Mpz	IMP		Rat	PMID:10212299|RGD:10047163
Cellular Component	GO:0005791	rough endoplasmic reticulum	Mpz	IDA		Rat	PMID:8789946|RGD:9685789
Biological Process	GO:0098743	cell aggregation	MPZ	IMP		Human	PMID:18337304
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	MPZ	IMP		Human	PMID:18337304
Biological Process	GO:0045217	cell-cell junction maintenance	Mpz	IMP	MGI:MGI:2384133	Mouse	PMID:11749037
Biological Process	GO:0042552	myelination	MPZ	IMP		Human	PMID:10545037
Biological Process	GO:0042552	myelination	Mpz	IMP	MGI:MGI:2384133	Mouse	PMID:20731761
Biological Process	GO:0043066	negative regulation of apoptotic process	Mpz	IMP		Rat	PMID:20552241|RGD:9685779

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern