Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0008408 | 3'-5' exonuclease activity | MRE11 | IDA | Human | PMID:9651580 | |
Molecular Function | GO:0008408 | 3'-5' exonuclease activity | MRE11 | IDA | Human | PMID:9705271 | |
Molecular Function | GO:0008409 | 5'-3' exonuclease activity | MRE11 | IDA | Human | PMID:29670289 | |
Molecular Function | GO:0045296 | cadherin binding | MRE11 | HDA | Human | PMID:25468996 | |
Molecular Function | GO:0003677 | DNA binding | MRE11 | IDA | Human | PMID:15790808 | |
Molecular Function | GO:0004520 | DNA endonuclease activity | MRE11 | IDA | Human | PMID:9705271 | |
Molecular Function | GO:0003678 | DNA helicase activity | MRE11 | IMP | Human | PMID:15790808 | |
Molecular Function | GO:0042802 | identical protein binding | MRE11 | IPI | UniProtKB:P49959 | Human | PMID:22078559 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:12419185 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P16104 | Human | PMID:12419185 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P15336 | Human | PMID:15916964 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P16104 | Human | PMID:16377563 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P03243-1 | Human | PMID:17428914 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:17500065 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P42858 | Human | PMID:17500595 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:17612497 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P16104 | Human | PMID:18583988 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q99708 | Human | PMID:18716619 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P16104 | Human | PMID:19234442 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q9BXW9 | Human | PMID:19609304 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q99708 | Human | PMID:21052091 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:22078559 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P16104 | Human | PMID:22157895 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60341 | Human | PMID:24529708 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O75943 | Human | PMID:24534091 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q61687 | Human | PMID:24651726 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:24981860 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q99708 | Human | PMID:25558984 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P03243-1 | Human | PMID:25772236 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:P38398,UniProtKB:Q99708,UniProtKB:Q9NVH0 | Human | PMID:26807646 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q99708 | Human | PMID:26807646 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q6NTE8 | Human | PMID:27568553 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q9Y3Z3 | Human | PMID:28834754 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q9Y3Z3 | Human | PMID:29670289 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:Q9NRR5 | Human | PMID:30612738 |
Molecular Function | GO:0005515 | protein binding | MRE11 | IPI | UniProtKB:O60934 | Human | PMID:9590181 |
Molecular Function | GO:0005515 | protein binding | Mre11a | IPI | UniProtKB:Q8BHZ5 | Mouse | MGI:MGI:6202149|PMID:30017584 |
Molecular Function | GO:0005515 | protein binding | Mre11a | IPI | UniProtKB:Q9R207 | Mouse | MGI:MGI:3770108|PMID:17429352 |
Molecular Function | GO:0005515 | protein binding | Mre11a | IPI | UniProtKB:Q9R207 | Mouse | MGI:MGI:3839734|PMID:18854157 |
Molecular Function | GO:0005515 | protein binding | Mre11 | IPI | UniProtKB:P03243 | Rat | PMID:18212738|RGD:2300253 |
Molecular Function | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity | MRE11 | IDA | Human | PMID:9705271 | |
Cellular Component | GO:0070533 | BRCA1-C complex | MRE11 | IPI | Human | PMID:16391231 | |
Cellular Component | GO:0000785 | chromatin | Mre11 | IDA | Rat | PMID:10855503|RGD:2300257 | |
Cellular Component | GO:0000781 | chromosome, telomeric region | MRE11 | IDA | Human | PMID:15149599 | |
Cellular Component | GO:0000781 | chromosome, telomeric region | MRE11 | IDA | Human | PMID:24270157 | |
Cellular Component | GO:0000781 | chromosome, telomeric region | MRE11 | IDA | Human | PMID:10811102 | |
Cellular Component | GO:0000781 | chromosome, telomeric region | MRE11 | HDA | Human | PMID:19135898 | |
Cellular Component | GO:0000781 | chromosome, telomeric region | Mre11a | IDA | Mouse | MGI:MGI:5705215|PMID:23444137 | |
Cellular Component | GO:0000794 | condensed nuclear chromosome | Mre11 | IDA | Rat | PMID:10855503|RGD:2300257 | |
Cellular Component | GO:0005737 | cytoplasm | MRE11 | IDA | Human | PMID:25468996 | |
Cellular Component | GO:0030870 | Mre11 complex | MRE11 | IPI | Human | PMID:31147924 | |
Cellular Component | GO:0030870 | Mre11 complex | MRE11 | IDA | Human | PMID:10888888 | |
Cellular Component | GO:0030870 | Mre11 complex | MRE11 | IDA | Human | PMID:19151086 | |
Cellular Component | GO:0005654 | nucleoplasm | MRE11 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005654 | nucleoplasm | Mre11 | IDA | Rat | PMID:16706843|RGD:2317719 | |
Cellular Component | GO:0005634 | nucleus | Mre11a | IDA | Mouse | PMID:15364958 | |
Cellular Component | GO:0005634 | nucleus | Mre11a | IDA | Mouse | PMID:12687013 | |
Cellular Component | GO:0005634 | nucleus | Mre11 | IDA | Rat | PMID:18212738|RGD:2300253 | |
Cellular Component | GO:0048471 | perinuclear region of cytoplasm | Mre11 | IDA | Rat | PMID:18212738|RGD:2300253 | |
Cellular Component | GO:0016605 | PML body | MRE11 | IDA | Human | PMID:10811102 | |
Cellular Component | GO:0016605 | PML body | Mre11a | IDA | Mouse | MGI:MGI:5705215|PMID:23444137 | |
Cellular Component | GO:0005657 | replication fork | MRE11 | IDA | Human | PMID:29290612 | |
Cellular Component | GO:0035861 | site of double-strand break | MRE11 | IDA | Human | PMID:15916964 | |
Cellular Component | GO:0035861 | site of double-strand break | MRE11 | IDA | Human | PMID:30612738 | |
Biological Process | GO:0008283 | cell population proliferation | Mre11a | IMP | Mouse | PMID:9224597 | |
Biological Process | GO:0051276 | chromosome organization | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:14690604 |
Biological Process | GO:0006974 | DNA damage response | MRE11 | IDA | Human | PMID:17500065 | |
Biological Process | GO:0006974 | DNA damage response | MRE11 | IDA | Human | PMID:29670289 | |
Biological Process | GO:0032508 | DNA duplex unwinding | MRE11 | IMP | Human | PMID:15790808 | |
Biological Process | GO:0110025 | DNA strand resection involved in replication fork processing | MRE11 | IDA | Human | PMID:29670289 | |
Biological Process | GO:0006302 | double-strand break repair | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:17291760 |
Biological Process | GO:0000724 | double-strand break repair via homologous recombination | MRE11 | IDA | Human | PMID:29670289 | |
Biological Process | GO:0000724 | double-strand break repair via homologous recombination | MRE11 | IDA | Human | PMID:30612738 | |
Biological Process | GO:0006303 | double-strand break repair via nonhomologous end joining | MRE11 | IDA | Human | PMID:9651580 | |
Biological Process | GO:0007507 | heart development | Mre11 | IEP | Rat | PMID:10908350|RGD:68816 | |
Biological Process | GO:0007129 | homologous chromosome pairing at meiosis | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:17291760 |
Biological Process | GO:0007095 | mitotic G2 DNA damage checkpoint signaling | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:14690604 |
Biological Process | GO:0031573 | mitotic intra-S DNA damage checkpoint signaling | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:14690604 |
Biological Process | GO:0031573 | mitotic intra-S DNA damage checkpoint signaling | Mre11a | IMP | MGI:MGI:3027036 | Mouse | PMID:18614044 |
Biological Process | GO:0043066 | negative regulation of apoptotic process | MRE11 | IMP | Human | PMID:16374507 | |
Biological Process | GO:0046597 | negative regulation of viral entry into host cell | Mre11 | IMP | Rat | PMID:22850678|RGD:8693392 | |
Biological Process | GO:0033674 | positive regulation of kinase activity | MRE11 | IDA | Human | PMID:15790808 | |
Biological Process | GO:0031954 | positive regulation of protein autophosphorylation | MRE11 | IDA | Human | PMID:15790808 | |
Biological Process | GO:0032206 | positive regulation of telomere maintenance | MRE11 | IMP | Human | PMID:16374507 | |
Biological Process | GO:0007062 | sister chromatid cohesion | MRE11 | IMP | Human | PMID:15917200 | |
Biological Process | GO:0031860 | telomeric 3' overhang formation | MRE11 | IMP | Human | PMID:16374507 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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