Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRLN
  • Mouse genes Mrln
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mrln

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	Mrln	IDA		Mouse	MGI:MGI:5614883|PMID:25640239
Molecular Function	GO:0005515	protein binding	Mrln	IPI	PR:O55143-1	Mouse	PMID:27923914
Molecular Function	GO:0005515	protein binding	Mrln	IPI	PR:Q64518	Mouse	PMID:25640239
Molecular Function	GO:0005515	protein binding	Mrln	IPI	PR:O55143	Mouse	PMID:25640239
Molecular Function	GO:0005515	protein binding	Mrln	IPI	PR:Q8R429	Mouse	PMID:25640239
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Mrln	IDA		Mouse	PMID:27923914
Cellular Component	GO:0033017	sarcoplasmic reticulum membrane	Mrln	IDA		Mouse	PMID:25640239
Biological Process	GO:1990036	calcium ion import into sarcoplasmic reticulum	Mrln	IMP		Mouse	PMID:25640239
Biological Process	GO:1901895	negative regulation of ATPase-coupled calcium transmembrane transporter activity	Mrln	IDA		Mouse	PMID:27923914
Biological Process	GO:1901877	negative regulation of calcium ion binding	Mrln	IDA		Mouse	PMID:27923914
Biological Process	GO:1902081	negative regulation of calcium ion import into sarcoplasmic reticulum	Mrln	IDA		Mouse	PMID:25640239
Biological Process	GO:1902081	negative regulation of calcium ion import into sarcoplasmic reticulum	Mrln	IMP		Mouse	PMID:25640239
Biological Process	GO:0009611	response to wounding	Mrln	IEP		Mouse	PMID:24917243

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern