Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MS4A1
  • Mouse genes Ms4a1
  • Rat genes Ms4a1
  • Zfish genes tmem176l.3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ms4a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	Ms4a1	IPI	RGD:2543	Rat	PMID:21349584|RGD:5131469
Molecular Function	GO:0042802	identical protein binding	MS4A1	IPI	UniProtKB:P11836	Human	PMID:32792392
Molecular Function	GO:0019865	immunoglobulin binding	MS4A1	IDA		Human	PMID:18474602
Molecular Function	GO:0023026	MHC class II protein complex binding	MS4A1	HDA		Human	PMID:20458337
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:A0PK05	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:A8MZ59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:O00590	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:P16871	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q15546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q5T7V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q6ZMZ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q86T13	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q96P31-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MS4A1	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	MS4A1	IDA		Human	PMID:3925015
Cellular Component	GO:0009897	external side of plasma membrane	Ms4a1	IDA		Mouse	PMID:19723499
Cellular Component	GO:0070062	extracellular exosome	MS4A1	HDA		Human	PMID:20458337
Cellular Component	GO:0005615	extracellular space	MS4A1	HDA		Human	PMID:22664934
Cellular Component	GO:0005654	nucleoplasm	MS4A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MS4A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MS4A1	IDA		Human	PMID:23874341
Cellular Component	GO:0044853	plasma membrane raft	MS4A1	IDA		Human	PMID:12920111
Biological Process	GO:0042113	B cell activation	MS4A1	IDA		Human	PMID:3925015
Biological Process	GO:0030183	B cell differentiation	MS4A1	IDA		Human	PMID:3925015
Biological Process	GO:0050853	B cell receptor signaling pathway	MS4A1	IDA		Human	PMID:18474602
Biological Process	GO:1902656	calcium ion import into cytosol	MS4A1	IDA		Human	PMID:7684739
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	Ms4a1	IDA		Mouse	MGI:MGI:3037466|PMID:14688067
Biological Process	GO:0051262	protein tetramerization	MS4A1	IDA		Human	PMID:18474602
Biological Process	GO:0051262	protein tetramerization	MS4A1	IDA		Human	PMID:7684739
Biological Process	GO:0009617	response to bacterium	Ms4a1	IEP		Mouse	PMID:23012479
Biological Process	GO:0002115	store-operated calcium entry	MS4A1	IMP		Human	PMID:12920111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern