Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MSH3
  • Mouse genes Msh3
  • Rat genes Msh3
  • Zfish genes msh3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Msh3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019237	centromeric DNA binding	Msh3	IDA		Mouse	PMID:16260499
Molecular Function	GO:0003684	damaged DNA binding	Msh3	IGI	MGI:MGI:1343961	Mouse	PMID:10545954
Molecular Function	GO:0032139	dinucleotide insertion or deletion binding	MSH3	IDA		Human	PMID:8942985
Molecular Function	GO:0032181	dinucleotide repeat insertion binding	MSH3	IDA		Human	PMID:8942985
Molecular Function	GO:0003677	DNA binding	Msh3	IGI	MGI:MGI:1343961	Mouse	PMID:10545954
Molecular Function	GO:0019899	enzyme binding	MSH3	IPI	UniProtKB:Q9UQ84	Human	PMID:11427529
Molecular Function	GO:0019899	enzyme binding	MSH3	IPI	UniProtKB:Q9NXL9	Human	PMID:26300262
Molecular Function	GO:0030983	mismatched DNA binding	MSH3	IDA		Human	PMID:8942985
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P12004	Human	PMID:11005803
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:14657349
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:16025128
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:19377479
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:22179786
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P12004	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P40692	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P40692	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P40692	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P12004	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:8942985
Molecular Function	GO:0005515	protein binding	MSH3	IPI	UniProtKB:P43246	Human	PMID:9774676
Molecular Function	GO:0032142	single guanine insertion binding	MSH3	IDA		Human	PMID:8942985
Molecular Function	GO:0003697	single-stranded DNA binding	MSH3	IDA		Human	PMID:11809883
Cellular Component	GO:0016020	membrane	MSH3	HDA		Human	PMID:19946888
Cellular Component	GO:0032302	MutSbeta complex	MSH3	IPI		Human	PMID:22179786
Cellular Component	GO:0032302	MutSbeta complex	MSH3	IDA		Human	PMID:8942985
Cellular Component	GO:0005634	nucleus	MSH3	IDA		Human	PMID:26300262
Biological Process	GO:0006281	DNA repair	MSH3	IDA		Human	PMID:8942985
Biological Process	GO:0043570	maintenance of DNA repeat elements	MSH3	IMP		Human	PMID:16388310
Biological Process	GO:0006298	mismatch repair	MSH3	IMP		Human	PMID:8782829
Biological Process	GO:0006298	mismatch repair	MSH3	IDA		Human	PMID:9677427
Biological Process	GO:0006298	mismatch repair	Msh3	IGI	MGI:MGI:1343961	Mouse	PMID:10706084
Biological Process	GO:0006298	mismatch repair	Msh3	IGI	MGI:MGI:1343961	Mouse	PMID:11691815
Biological Process	GO:0006298	mismatch repair	Msh3	IMP	MGI:MGI:1858056	Mouse	PMID:10706084
Biological Process	GO:0006298	mismatch repair	Msh3	IGI	MGI:MGI:88039	Mouse	PMID:11691815
Biological Process	GO:0006298	mismatch repair	Msh3	IGI	MGI:MGI:101816	Mouse	PMID:16728433
Biological Process	GO:0006298	mismatch repair	Msh3	IMP	MGI:MGI:1858056	Mouse	PMID:16728433
Biological Process	GO:0006298	mismatch repair	Msh3	IGI	MGI:MGI:1343961	Mouse	PMID:16728433
Biological Process	GO:0045910	negative regulation of DNA recombination	MSH3	IDA		Human	PMID:17715146
Biological Process	GO:0051096	positive regulation of helicase activity	MSH3	IDA		Human	PMID:17715146
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	Msh3	IMP	MGI:MGI:1858056	Mouse	PMID:15238604
Biological Process	GO:0007283	spermatogenesis	Msh3	IEP		Rat	PMID:10644444|RGD:727288

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern