Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MSN
  • Mouse genes Msn
  • Rat genes Msn
  • Zfish genes msna,msnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Msn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Msn	IDA		Rat	PMID:10945828|RGD:727296
Molecular Function	GO:0050839	cell adhesion molecule binding	MSN	IPI	UniProtKB:P19320	Human	PMID:12082081
Molecular Function	GO:0050839	cell adhesion molecule binding	MSN	IPI	UniProtKB:P32942	Human	PMID:12082081
Molecular Function	GO:0003725	double-stranded RNA binding	MSN	IDA		Human	PMID:21266579
Molecular Function	GO:0019899	enzyme binding	MSN	IPI	UniProtKB:P0C0G7	Human	PMID:15922359
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q9EP53	Human	PMID:10806479
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:O14745	Human	PMID:15020681
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P97820	Human	PMID:16938849
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q86YL7	Human	PMID:17046996
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q96T49	Human	PMID:18586956
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:20642453
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q9H270	Human	PMID:21148287
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:22363216
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:22952686
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:23241358
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P16070	Human	PMID:23855374
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:24351927
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:24695735
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S006	Human	PMID:24794857
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:24904275
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:25009464
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:27357661
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P25791-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P0DTC2	Human	PMID:34504087
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:P15311	Human	PMID:7844168
Molecular Function	GO:0005515	protein binding	MSN	IPI	UniProtKB:O14745	Human	PMID:9430655
Molecular Function	GO:0005515	protein binding	Msn	IPI	UniProtKB:P13838|UniProtKB:P15379|UniProtKB:P35330	Mouse	MGI:MGI:6115186|PMID:9472040
Molecular Function	GO:0005515	protein binding	Msn	IPI	PR:Q9JLI7	Mouse	PMID:31146259
Molecular Function	GO:0019901	protein kinase binding	MSN	IPI	UniProtKB:O94804	Human	PMID:19255442
Molecular Function	GO:0005102	signaling receptor binding	MSN	IPI	UniProtKB:Q9NPY3	Human	PMID:15819698
Cellular Component	GO:0045177	apical part of cell	MSN	IDA		Human	PMID:12082081
Cellular Component	GO:0045177	apical part of cell	Msn	IDA		Mouse	PMID:9890997
Cellular Component	GO:0016324	apical plasma membrane	MSN	IDA		Human	PMID:24862762
Cellular Component	GO:0016324	apical plasma membrane	MSN	IDA		Human	PMID:25775275
Cellular Component	GO:0016324	apical plasma membrane	Msn	IDA		Mouse	PMID:14625387
Cellular Component	GO:0016323	basolateral plasma membrane	Msn	IDA		Mouse	PMID:14625387
Cellular Component	GO:0072562	blood microparticle	MSN	HDA		Human	PMID:22516433
Cellular Component	GO:0071944	cell periphery	MSN	IDA		Human	PMID:22291017
Cellular Component	GO:0009986	cell surface	MSN	IDA		Human	PMID:15922359
Cellular Component	GO:0009986	cell surface	Msn	IDA		Rat	PMID:10945828|RGD:727296
Cellular Component	GO:0051286	cell tip	Msn	IDA		Rat	PMID:17061246|RGD:7207800
Cellular Component	GO:0005737	cytoplasm	MSN	HDA		Human	PMID:16791210
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Msn	IDA		Rat	PMID:10945828|RGD:727296
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	MSN	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MSN	HDA		Human	PMID:16502470
Cellular Component	GO:0030175	filopodium	MSN	IDA		Human	PMID:12082081
Cellular Component	GO:0030175	filopodium	MSN	IDA		Human	PMID:24065547
Cellular Component	GO:0031527	filopodium membrane	Msn	IDA		Rat	PMID:10945828|RGD:727296
Cellular Component	GO:0005925	focal adhesion	MSN	IDA		Human	PMID:21282464
Cellular Component	GO:0005925	focal adhesion	MSN	HDA		Human	PMID:21423176
Cellular Component	GO:0005902	microvillus	MSN	IDA		Human	PMID:12082081
Cellular Component	GO:0005902	microvillus	Msn	IDA		Mouse	MGI:MGI:6115186|PMID:9472040
Cellular Component	GO:0043209	myelin sheath	Msn	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005634	nucleus	MSN	HDA		Human	PMID:16791210
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MSN	IDA		Human	PMID:24862762
Cellular Component	GO:0005886	plasma membrane	MSN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031143	pseudopodium	MSN	IDA		Human	PMID:24065547
Cellular Component	GO:0030667	secretory granule membrane	Msn	IDA		Rat	PMID:10945828|RGD:727296
Cellular Component	GO:0030315	T-tubule	Msn	IDA		Rat	PMID:19028724|RGD:7207798
Cellular Component	GO:0001931	uropod	Msn	IDA		Mouse	PMID:11728336
Cellular Component	GO:0031982	vesicle	MSN	HDA		Human	PMID:19190083
Biological Process	GO:0072554	blood vessel lumenization	msna	IMP	ZFIN:ZDB-MRPHLNO-100908-7	Zfish	PMID:20736288
Biological Process	GO:0071394	cellular response to testosterone stimulus	MSN	IDA		Human	PMID:24065547
Biological Process	GO:0007492	endoderm development	msna	IDA		Zfish	PMID:17993262
Biological Process	GO:0061028	establishment of endothelial barrier	MSN	IGI	UniProtKB:P15311|UniProtKB:P35241	Human	PMID:23264465
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	MSN	IMP		Human	PMID:24862762
Biological Process	GO:0022612	gland morphogenesis	MSN	IMP		Human	PMID:24862762
Biological Process	GO:0001771	immunological synapse formation	MSN	IDA		Human	PMID:27405666
Biological Process	GO:0007159	leukocyte cell-cell adhesion	MSN	IEP		Human	PMID:12082081
Biological Process	GO:0050900	leukocyte migration	MSN	IEP		Human	PMID:12082081
Biological Process	GO:0022614	membrane to membrane docking	MSN	IEP		Human	PMID:12082081
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	MSN	IGI	UniProtKB:P15311|UniProtKB:P35241	Human	PMID:21148287
Biological Process	GO:0010628	positive regulation of gene expression	MSN	IGI	UniProtKB:Q96S97	Human	PMID:23264465
Biological Process	GO:0071803	positive regulation of podosome assembly	Msn	IDA		Mouse	PMID:24127566
Biological Process	GO:0045732	positive regulation of protein catabolic process	MSN	IGI	UniProtKB:P15311|UniProtKB:P35241	Human	PMID:21148287
Biological Process	GO:1902966	positive regulation of protein localization to early endosome	MSN	IGI	UniProtKB:P15311|UniProtKB:P35241	Human	PMID:21148287
Biological Process	GO:0008360	regulation of cell shape	MSN	IMP		Human	PMID:24862762
Biological Process	GO:0008361	regulation of cell size	MSN	IMP		Human	PMID:24862762
Biological Process	GO:2000401	regulation of lymphocyte migration	MSN	IMP		Human	PMID:19255442
Biological Process	GO:1902115	regulation of organelle assembly	MSN	IGI	UniProtKB:P15311|UniProtKB:P35241	Human	PMID:21148287
Biological Process	GO:0070489	T cell aggregation	MSN	IDA		Human	PMID:27405666
Biological Process	GO:0072678	T cell migration	MSN	IDA		Human	PMID:27405666
Biological Process	GO:0042098	T cell proliferation	MSN	IDA		Human	PMID:27405666

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern