Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Msx1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MSX1
- Mouse genes Msx1
- Rat genes Msx1
- Zfish genes msx1a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Msx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Msx1	IDA		Mouse	PMID:27741242
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Msx1	IDA		Mouse	PMID:22071108
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Msx1	IDA		Mouse	PMID:18285513
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Msx1	IDA		Mouse	MGI:MGI:80319\|PMID:8861098
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Msx1	IMP		Mouse	MGI:MGI:80319\|PMID:8861098
Molecular Function	GO:0002039	p53 binding	MSX1	IPI	UniProtKB:P04637	Human	PMID:15705871
Molecular Function	GO:0005515	protein binding	MSX1	IPI	UniProtKB:Q93062-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Msx1	IPI	UniProtKB:P43276	Mouse	MGI:MGI:3047475\|PMID:15192231
Molecular Function	GO:0005515	protein binding	Msx1	IPI	UniProtKB:P25233	Mouse	MGI:MGI:3828407\|PMID:15272023
Molecular Function	GO:0005515	protein binding	Msx1	IPI	PR:Q9Z0S2	Mouse	PMID:9697309
Molecular Function	GO:0005515	protein binding	Msx1	IPI	PR:Q9JM73	Mouse	PMID:17030628
Molecular Function	GO:0005515	protein binding	Msx1	IPI	PR:Q8VIM5	Mouse	PMID:17030628
Molecular Function	GO:0005515	protein binding	Msx1	IPI	PR:P62960	Mouse	PMID:20004191
Molecular Function	GO:0005515	protein binding	Msx1	IPI	PR:P47242	Mouse	PMID:15721141
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Msx1	IMP		Mouse	MGI:MGI:80319\|PMID:8861098
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Msx1	IDA		Mouse	PMID:7916326
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Msx1	IDA		Mouse	PMID:9369446
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Msx1	IDA		Mouse	PMID:15192231
Molecular Function	GO:0043565	sequence-specific DNA binding	Msx1	IDA		Mouse	PMID:8858134
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MSX1	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	MSX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MSX1	IDA		Human	PMID:15705871
Cellular Component	GO:0005634	nucleus	Msx1	IGI	MGI:MGI:99146	Mouse	PMID:20004191
Cellular Component	GO:0005667	transcription regulator complex	Msx1	IPI	PR:P70326	Mouse	PMID:18285513
Cellular Component	GO:0005667	transcription regulator complex	Msx1	IPI	UniProtKB:Q5SSP7	Mouse	PMID:18285513
Biological Process	GO:0090427	activation of meiosis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:22071108
Biological Process	GO:0009952	anterior/posterior pattern specification	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0030509	BMP signaling pathway	Msx1	IDA		Mouse	PMID:18590716
Biological Process	GO:0030509	BMP signaling pathway	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17601530
Biological Process	GO:0030509	BMP signaling pathway	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:18667074
Biological Process	GO:0061312	BMP signaling pathway involved in heart development	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:18667074
Biological Process	GO:0060349	bone morphogenesis	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:12489152
Biological Process	GO:0060349	bone morphogenesis	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:16330189
Biological Process	GO:0060349	bone morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17693062
Biological Process	GO:0051216	cartilage development	Msx1	IMP		Rat	PMID:10332146\|RGD:1600462
Biological Process	GO:0060536	cartilage morphogenesis	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:12489152
Biological Process	GO:0000902	cell morphogenesis	MSX1	IDA		Human	PMID:15705871
Biological Process	GO:0071316	cellular response to nicotine	Msx1	IEP		Rat	PMID:20339300\|RGD:5132605
Biological Process	GO:0042733	embryonic digit morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0030326	embryonic limb morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:19422820
Biological Process	GO:0030326	embryonic limb morphogenesis	Msx1	IGI	MGI:MGI:98297	Mouse	PMID:19422820
Biological Process	GO:0030326	embryonic limb morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:15930102
Biological Process	GO:0035880	embryonic nail plate morphogenesis	MSX1	IMP		Human	PMID:11369996
Biological Process	GO:0035880	embryonic nail plate morphogenesis	Msx1	IMP		Mouse	MGI:MGI:3688967\|PMID:11369996
Biological Process	GO:0035880	embryonic nail plate morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0001837	epithelial to mesenchymal transition	Msx1	IMP		Mouse	MGI:MGI:4418636\|PMID:11023873
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:18667074
Biological Process	GO:0060325	face morphogenesis	MSX1	IMP		Human	PMID:10742093
Biological Process	GO:0060325	face morphogenesis	MSX1	IMP		Human	PMID:11332647
Biological Process	GO:0060325	face morphogenesis	MSX1	IMP		Human	PMID:12651933
Biological Process	GO:0060325	face morphogenesis	Msx1	IMP		Mouse	MGI:MGI:3688967\|PMID:11369996
Biological Process	GO:0060325	face morphogenesis	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:16330189
Biological Process	GO:0060325	face morphogenesis	Msx1	IGI	MGI:MGI:97493	Mouse	PMID:20123092
Biological Process	GO:0030900	forebrain development	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:15217086
Biological Process	GO:0030900	forebrain development	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:15188430
Biological Process	GO:0007507	heart development	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17601530
Biological Process	GO:0003007	heart morphogenesis	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17601530
Biological Process	GO:0001701	in utero embryonic development	Msx1	IMP	MGI:MGI:1926386	Mouse	PMID:17601530
Biological Process	GO:0061180	mammary gland epithelium development	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:10742104
Biological Process	GO:0097152	mesenchymal cell apoptotic process	Msx1	IGI	MGI:MGI:98297	Mouse	PMID:19422820
Biological Process	GO:0097152	mesenchymal cell apoptotic process	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:19422820
Biological Process	GO:0010463	mesenchymal cell proliferation	Msx1	IMP		Mouse	MGI:MGI:4418636\|PMID:11023873
Biological Process	GO:0030901	midbrain development	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:15188430
Biological Process	GO:0042474	middle ear morphogenesis	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:16330189
Biological Process	GO:0007517	muscle organ development	Msx1	IPI	UniProtKB:P43276	Mouse	PMID:15192231
Biological Process	GO:0043066	negative regulation of apoptotic process	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17601530
Biological Process	GO:0030308	negative regulation of cell growth	MSX1	IDA		Human	PMID:15705871
Biological Process	GO:0008285	negative regulation of cell population proliferation	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17601530
Biological Process	GO:0043392	negative regulation of DNA binding	Msx1	IDA		Mouse	PMID:17030628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Msx1	IDA		Mouse	PMID:15192231
Biological Process	GO:0051154	negative regulation of striated muscle cell differentiation	Msx1	IDA		Mouse	PMID:20004191
Biological Process	GO:0051154	negative regulation of striated muscle cell differentiation	Msx1	IGI	MGI:MGI:99146	Mouse	PMID:20004191
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IDA		Mouse	MGI:MGI:80319\|PMID:8861098
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IDA		Mouse	PMID:15192231
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IDA		Mouse	PMID:9369446
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IDA		Mouse	PMID:16002402
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:98494	Mouse	PMID:18285513
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IDA		Mouse	PMID:20004191
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:99146	Mouse	PMID:20004191
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:2137495	Mouse	PMID:17030628
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	Msx1	IGI	MGI:MGI:96785	Mouse	PMID:9697309
Biological Process	GO:0042476	odontogenesis	Msx1	IMP		Mouse	MGI:MGI:4418636\|PMID:11023873
Biological Process	GO:0042476	odontogenesis	Msx1	IGI	MGI:MGI:97493	Mouse	PMID:20123092
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	MSX1	IMP		Human	PMID:10742093
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	MSX1	IMP		Human	PMID:11369996
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	MSX1	IMP		Human	PMID:8696335
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Msx1	IMP		Mouse	MGI:MGI:3688967\|PMID:11369996
Biological Process	GO:0043049	otic placode formation	msx1a	IGI	ZFIN:ZDB-MRPHLNO-070215-1,ZFIN:ZDB-MRPHLNO-070215-3	Zfish	PMID:16631154
Biological Process	GO:0021983	pituitary gland development	Msx1	IEP		Rat	PMID:16451220\|RGD:5132608
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:18667074
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	MSX1	IDA		Human	PMID:15705871
Biological Process	GO:2001055	positive regulation of mesenchymal cell apoptotic process	Msx1	IGI	MGI:MGI:98297	Mouse	PMID:19422820
Biological Process	GO:2001055	positive regulation of mesenchymal cell apoptotic process	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:19422820
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:95516	Mouse	PMID:8898217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:95515	Mouse	PMID:8898217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:95518	Mouse	PMID:8898217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:88180	Mouse	PMID:10340755
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IMP	MGI:MGI:1926386	Mouse	PMID:8898217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:98297	Mouse	PMID:10340755
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Msx1	IGI	MGI:MGI:97168	Mouse	PMID:8898217
Biological Process	GO:0034504	protein localization to nucleus	MSX1	IDA		Human	PMID:15705871
Biological Process	GO:0050821	protein stabilization	MSX1	IDA		Human	PMID:15705871
Biological Process	GO:0042481	regulation of odontogenesis	Msx1	IGI	MGI:MGI:97493	Mouse	PMID:20123092
Biological Process	GO:0060021	roof of mouth development	Msx1	IMP	MGI:MGI:1933766	Mouse	PMID:16330189
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:21465616
Biological Process	GO:0048863	stem cell differentiation	Msx1	IGI	MGI:MGI:97169	Mouse	PMID:17693062
Biological Process	GO:0006366	transcription by RNA polymerase II	Msx1	IMP	MGI:MGI:1926386	Mouse	PMID:8898217

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.