Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTAP
  • Mouse genes Mtap
  • Rat genes Mtap
  • Zfish genes mtap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MTAP	IPI	UniProtKB:Q9H3R5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MTAP	IPI	UniProtKB:Q9P0I2	Human	PMID:32296183
Molecular Function	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity	Mtap	IDA		Rat	PMID:6401802|RGD:2317956
Molecular Function	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity	Mtap	IDA		Rat	PMID:6766069|RGD:7242934
Cellular Component	GO:0005829	cytosol	MTAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	MTAP	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	MTAP	IDA		Human	GO_REF:0000052
Biological Process	GO:0032259	methylation	Mtap	IMP	MGI:MGI:3514132	Mouse	PMID:22952318
Biological Process	GO:0033574	response to testosterone	Mtap	IEP		Rat	PMID:6774734|RGD:2317950

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern