Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTCL1
  • Mouse genes Mtcl1
  • Rat genes Mtcl1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtcl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	MTCL1	IDA		Human	PMID:23902687
Molecular Function	GO:0008017	microtubule binding	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Molecular Function	GO:0005515	protein binding	Mtcl1	IPI	UniProtKB:Q7KZI7	Mouse	MGI:MGI:5553212|PMID:23902687
Molecular Function	GO:0042803	protein homodimerization activity	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Molecular Function	GO:0003723	RNA binding	MTCL1	HDA		Human	PMID:22658674
Cellular Component	GO:0016327	apicolateral plasma membrane	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Cellular Component	GO:0005856	cytoskeleton	MTCL1	IDA		Human	PMID:23902687
Cellular Component	GO:0005856	cytoskeleton	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Cellular Component	GO:0016328	lateral plasma membrane	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Cellular Component	GO:0097427	microtubule bundle	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Cellular Component	GO:0030496	midbody	MTCL1	IDA		Human	PMID:23902687
Cellular Component	GO:0030496	midbody	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Cellular Component	GO:0000922	spindle pole	MTCL1	IDA		Human	PMID:23902687
Cellular Component	GO:0000922	spindle pole	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Biological Process	GO:0001578	microtubule bundle formation	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Mtcl1	IDA		Mouse	MGI:MGI:5553212|PMID:23902687

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern