Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTF1
  • Mouse genes Mtf1
  • Rat genes Mtf1
  • Zfish genes mtf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	MTF1	IDA		Human	PMID:15735762
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mtf1	IDA		Mouse	PMID:10952993
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mtf1	IDA		Mouse	PMID:16886906
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mtf1	IDA		Mouse	PMID:9582278
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Mtf1	IDA		Mouse	PMID:10931824
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MTF1	IDA		Human	PMID:9582278
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mtf1	IDA		Mouse	PMID:10952993
Molecular Function	GO:0035035	histone acetyltransferase binding	Mtf1	IPI	PR:B2RWS6	Mouse	PMID:18605988
Molecular Function	GO:0005515	protein binding	MTF1	IPI	UniProtKB:Q9BXS5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MTF1	IPI	UniProtKB:Q9BXS5	Human	PMID:19060904
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MTF1	IDA		Human	PMID:9582278
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Mtf1	IDA		Mouse	PMID:18605988
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MTF1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Mtf1	IDA		Mouse	MGI:MGI:5577232|PMID:24529376
Cellular Component	GO:0005737	cytoplasm	mtf1	IDA		Zfish	PMID:17269467
Cellular Component	GO:0005654	nucleoplasm	MTF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mtf1	IDA		Mouse	MGI:MGI:5577232|PMID:24529376
Cellular Component	GO:0005634	nucleus	mtf1	IDA		Zfish	PMID:17269467
Biological Process	GO:1990079	cartilage homeostasis	Mtf1	IMP		Mouse	MGI:MGI:5577232|PMID:24529376
Biological Process	GO:0071276	cellular response to cadmium ion	mtf1	IDA		Zfish	PMID:24751692
Biological Process	GO:0071294	cellular response to zinc ion	Mtf1	IDA		Mouse	MGI:MGI:5577232|PMID:24529376
Biological Process	GO:0071294	cellular response to zinc ion	mtf1	IDA		Zfish	PMID:24751692
Biological Process	GO:0006351	DNA-templated transcription	Mtf1	IDA		Mouse	MGI:MGI:5577232|PMID:24529376
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mtf1	IMP	MGI:MGI:2182939	Mouse	PMID:10952993
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MTF1	IDA		Human	PMID:9582278
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mtf1	IDA		Mouse	PMID:9582278
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mtf1	IDA		Mouse	PMID:10931824
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mtf1	IDA		Rat	PMID:23716681|RGD:8554514
Biological Process	GO:0046686	response to cadmium ion	Mtf1	IMP	MGI:MGI:2182939	Mouse	PMID:9582278
Biological Process	GO:0046686	response to cadmium ion	mtf1	IDA		Zfish	PMID:17269467
Biological Process	GO:0046686	response to cadmium ion	mtf1	IGI	ZFIN:ZDB-GENE-020508-1	Zfish	PMID:24751692
Biological Process	GO:0006979	response to oxidative stress	Mtf1	IMP	MGI:MGI:2182939	Mouse	PMID:9582278
Biological Process	GO:0010043	response to zinc ion	mtf1	IGI	ZFIN:ZDB-GENE-030131-5773	Zfish	PMID:24751692
Biological Process	GO:0010043	response to zinc ion	mtf1	IDA		Zfish	PMID:17269467

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern