Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTF2
  • Mouse genes Mtf2
  • Rat genes Mtf2
  • Zfish genes mtf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035064	methylated histone binding	MTF2	IDA		Human	PMID:23142980
Molecular Function	GO:0035064	methylated histone binding	Mtf2	IDA		Mouse	MGI:MGI:5487476|PMID:23104054
Molecular Function	GO:0005515	protein binding	Mtf2	IPI	UniProtKB:P70351|UniProtKB:Q61188|UniProtKB:Q921E6	Mouse	MGI:MGI:4436818|PMID:20064376
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Mtf2	IDA		Mouse	MGI:MGI:68306|PMID:7772254
Molecular Function	GO:0001222	transcription corepressor binding	MTF2	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0005737	cytoplasm	MTF2	IDA		Human	PMID:8619255
Cellular Component	GO:0035098	ESC/E(Z) complex	Mtf2	IDA		Mouse	MGI:MGI:4429983|PMID:20144788
Cellular Component	GO:0005654	nucleoplasm	MTF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MTF2	IDA		Human	PMID:8619255
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Mtf2	IEP		Mouse	PMID:20439489
Biological Process	GO:0040029	epigenetic regulation of gene expression	Mtf2	IMP		Mouse	MGI:MGI:4946172|PMID:21059868
Biological Process	GO:0040029	epigenetic regulation of gene expression	Mtf2	IMP		Mouse	MGI:MGI:4429983|PMID:20144788
Biological Process	GO:0007379	segment specification	Mtf2	IMP		Mouse	MGI:MGI:4946172|PMID:21059868
Biological Process	GO:0048863	stem cell differentiation	Mtf2	IMP		Mouse	MGI:MGI:4429983|PMID:20144788
Biological Process	GO:0019827	stem cell population maintenance	Mtf2	IMP		Mouse	MGI:MGI:4429983|PMID:20144788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern