Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTHFD2L
  • Mouse genes Mthfd2l
  • Rat genes Mthfd2l
  • Zfish genes mthfd2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mthfd2l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	Mthfd2l	IDA		Rat	PMID:24733394|RGD:150521648
Molecular Function	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity	Mthfd2l	IDA		Rat	PMID:24733394|RGD:150521648
Molecular Function	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Mthfd2l	IDA		Rat	PMID:21163947|RGD:7244288
Molecular Function	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Mthfd2l	IDA		Rat	PMID:24733394|RGD:150521648
Cellular Component	GO:0005743	mitochondrial inner membrane	Mthfd2l	IDA		Rat	PMID:21163947|RGD:7244288
Cellular Component	GO:0005759	mitochondrial matrix	Mthfd2l	IDA		Rat	PMID:21163947|RGD:7244288
Biological Process	GO:0009256	10-formyltetrahydrofolate metabolic process	Mthfd2l	IDA		Rat	PMID:21163947|RGD:7244288
Biological Process	GO:0035999	tetrahydrofolate interconversion	Mthfd2l	IDA		Rat	PMID:21163947|RGD:7244288
Biological Process	GO:0035999	tetrahydrofolate interconversion	Mthfd2l	IDA		Rat	PMID:24733394|RGD:150521648

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern