Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTNR1B
  • Mouse genes Mtnr1b
  • Rat genes Mtnr1b
  • Zfish genes mtnr1ba,mtnr1bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtnr1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:O76081	Human	PMID:20859254
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:P48039	Human	PMID:20859254
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:P28335	Human	PMID:25770211
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:Q14669	Human	PMID:26514267
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:Q8IZ08	Human	PMID:28827538
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:Q9BZJ7	Human	PMID:28827538
Molecular Function	GO:0005515	protein binding	MTNR1B	IPI	UniProtKB:Q9BZJ8	Human	PMID:28827538
Biological Process	GO:0043010	camera-type eye development	Mtnr1b	IEP		Rat	PMID:12890503|RGD:9588674
Biological Process	GO:0042593	glucose homeostasis	MTNR1B	IMP		Human	PMID:20668700
Biological Process	GO:0010754	negative regulation of cGMP-mediated signaling	Mtnr1b	IMP		Rat	PMID:18363673|RGD:9588673
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Mtnr1b	IMP		Rat	PMID:14675130|RGD:9588672
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	Mtnr1b	IDA		Rat	PMID:14962062|RGD:9588668
Biological Process	GO:0046676	negative regulation of insulin secretion	Mtnr1b	IMP		Rat	PMID:18363673|RGD:9588673
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Mtnr1b	IDA		Rat	PMID:14962062|RGD:9588668
Biological Process	GO:0051970	negative regulation of transmission of nerve impulse	Mtnr1b	IMP		Rat	PMID:15082174|RGD:9588675
Biological Process	GO:0045906	negative regulation of vasoconstriction	Mtnr1b	IMP		Rat	PMID:10199853|RGD:9588661
Biological Process	GO:0042753	positive regulation of circadian rhythm	Mtnr1b	IDA		Rat	PMID:12643943|RGD:9588678
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Mtnr1b	IDA		Rat	PMID:19429170|RGD:9588660
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Mtnr1b	IMP		Rat	PMID:22171046|RGD:9588665
Biological Process	GO:0051971	positive regulation of transmission of nerve impulse	Mtnr1b	IDA		Rat	PMID:22171046|RGD:9588665
Biological Process	GO:0050796	regulation of insulin secretion	MTNR1B	IMP		Human	PMID:20668700
Biological Process	GO:0098908	regulation of neuronal action potential	Mtnr1b	IMP		Rat	PMID:21094224|RGD:9588677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern