Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTPAP
  • Mouse genes Mtpap
  • Rat genes Mtpap
  • Zfish genes mtpap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtpap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	MTPAP	IDA		Human	PMID:21292163
Molecular Function	GO:0042802	identical protein binding	MTPAP	IPI	UniProtKB:Q9NVV4	Human	PMID:21292163
Molecular Function	GO:0000287	magnesium ion binding	MTPAP	IDA		Human	PMID:21292163
Molecular Function	GO:0030145	manganese ion binding	MTPAP	IDA		Human	PMID:21292163
Molecular Function	GO:1990817	poly(A) RNA polymerase activity	MTPAP	IDA		Human	PMID:21292163
Molecular Function	GO:0005515	protein binding	MTPAP	IPI	UniProtKB:Q13137	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	MTPAP	IPI	UniProtKB:Q9QYP6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	MTPAP	IPI	UniProtKB:Q9UHD2	Human	PMID:21903422
Molecular Function	GO:0042803	protein homodimerization activity	MTPAP	IPI	UniProtKB:Q9NVV4	Human	PMID:21292163
Molecular Function	GO:0003723	RNA binding	MTPAP	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	MTPAP	HDA		Human	PMID:22681889
Molecular Function	GO:0002134	UTP binding	MTPAP	IDA		Human	PMID:21292163
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MTPAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	MTPAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Mtpap	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	MTPAP	IDA		Human	GO_REF:0000052
Biological Process	GO:0071044	histone mRNA catabolic process	MTPAP	IMP		Human	PMID:18172165
Biological Process	GO:0006378	mRNA polyadenylation	MTPAP	IDA		Human	PMID:21292163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern