Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTPN
  • Mouse genes Mtpn
  • Rat genes Mtpn
  • Zfish genes mtpn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtpn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Mtpn	IPI	UniProtKB:Q5XI32	Rat	PMID:15845376|RGD:8554492
Molecular Function	GO:0043565	sequence-specific DNA binding	Mtpn	IDA		Rat	PMID:12031792|RGD:1581046
Cellular Component	GO:0030424	axon	Mtpn	IDA		Rat	PMID:12419325|RGD:632799
Cellular Component	GO:0005737	cytoplasm	Mtpn	IDA		Rat	PMID:12419325|RGD:632799
Cellular Component	GO:0005737	cytoplasm	Mtpn	IDA		Rat	PMID:17041682|RGD:1582572
Cellular Component	GO:0005829	cytosol	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Cellular Component	GO:0008290	F-actin capping protein complex	MTPN	IDA		Human	PMID:16895918
Cellular Component	GO:0005634	nucleus	Mtpn	IDA		Rat	PMID:12031792|RGD:1581046
Cellular Component	GO:0005634	nucleus	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:0006584	catecholamine metabolic process	Mtpn	IEP		Rat	PMID:12051753|RGD:625450
Biological Process	GO:0071260	cellular response to mechanical stimulus	Mtpn	IEP		Rat	PMID:12031792|RGD:1581046
Biological Process	GO:0021707	cerebellar granule cell differentiation	Mtpn	IEP		Rat	PMID:8144589|RGD:632797
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	MTPN	IMP		Human	PMID:10329199
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Mtpn	IMP		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:0030307	positive regulation of cell growth	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:0010557	positive regulation of macromolecule biosynthetic process	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:0051247	positive regulation of protein metabolic process	Mtpn	IDA		Rat	PMID:18693253|RGD:8553542
Biological Process	GO:2000812	regulation of barbed-end actin filament capping	MTPN	IDA		Human	PMID:16895918
Biological Process	GO:0008361	regulation of cell size	MTPN	IDA		Human	PMID:10329199
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Mtpn	IEP		Rat	PMID:12467730|RGD:632798
Biological Process	GO:0051146	striated muscle cell differentiation	Mtpn	IEP		Rat	PMID:12467730|RGD:632798

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern