Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTSS1
  • Mouse genes Mtss1
  • Rat genes Mtss1
  • Zfish genes mtss1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtss1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Mtss1	IDA		Mouse	PMID:12482861
Molecular Function	GO:0051015	actin filament binding	Mtss1	IDA		Mouse	PMID:21406566
Molecular Function	GO:0003785	actin monomer binding	MTSS1	IDA		Human	PMID:12570871
Molecular Function	GO:0042802	identical protein binding	MTSS1	IPI	UniProtKB:O43312	Human	PMID:14752106
Molecular Function	GO:0042802	identical protein binding	Mtss1	IPI	UniProtKB:Q8R1S4	Mouse	MGI:MGI:5921637|PMID:17292833
Molecular Function	GO:0005515	protein binding	MTSS1	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	MTSS1	IPI	UniProtKB:Q60598	Human	PMID:15688017
Molecular Function	GO:0005515	protein binding	Mtss1	IPI	UniProtKB:Q62074|UniProtKB:Q99NH2-1	Mouse	MGI:MGI:5474897|PMID:23446420
Molecular Function	GO:0005102	signaling receptor binding	MTSS1	IPI	UniProtKB:P23468	Human	PMID:12570871
Cellular Component	GO:0015629	actin cytoskeleton	MTSS1	IDA		Human	PMID:12570871
Cellular Component	GO:0005912	adherens junction	Mtss1	IDA		Mouse	PMID:21406566
Cellular Component	GO:0005737	cytoplasm	Mtss1	IDA		Mouse	PMID:12482861
Biological Process	GO:0007015	actin filament organization	Mtss1	IDA		Mouse	PMID:12482861
Biological Process	GO:0030041	actin filament polymerization	Mtss1	IDA		Mouse	PMID:12482861
Biological Process	GO:0034334	adherens junction maintenance	Mtss1	IMP	MGI:MGI:5319219	Mouse	PMID:21406566
Biological Process	GO:0030282	bone mineralization	Mtss1	IMP	MGI:MGI:5319219	Mouse	PMID:21406566
Biological Process	GO:0071498	cellular response to fluid shear stress	Mtss1	IDA		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis	Mtss1	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0072102	glomerulus morphogenesis	Mtss1	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0001701	in utero embryonic development	Mtss1	IGI	MGI:MGI:105373	Mouse	PMID:21406566
Biological Process	GO:0010960	magnesium ion homeostasis	Mtss1	IMP	MGI:MGI:5319219	Mouse	PMID:21406566
Biological Process	GO:0072170	metanephric tubule development	Mtss1	IMP	MGI:MGI:5319219	Mouse	PMID:21406566
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Mtss1	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0072160	nephron tubule epithelial cell differentiation	Mtss1	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	Mtss1	IMP	MGI:MGI:5319219	Mouse	PMID:21406566
Biological Process	GO:0061333	renal tubule morphogenesis	Mtss1	IMP		Mouse	MGI:MGI:4440396|PMID:20181743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern