Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTTP
  • Mouse genes Mttp
  • Rat genes Mttp
  • Zfish genes mttp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mttp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034185	apolipoprotein binding	Mttp	IPI	RGD:2129	Rat	PMID:11830580|RGD:1582567
Molecular Function	GO:1902388	ceramide 1-phosphate transfer activity	MTTP	IDA		Human	PMID:23475612
Molecular Function	GO:0120020	cholesterol transfer activity	MTTP	IDA		Human	PMID:15897609
Molecular Function	GO:0120020	cholesterol transfer activity	MTTP	IDA		Human	PMID:16478722
Molecular Function	GO:0120020	cholesterol transfer activity	MTTP	IMP		Human	PMID:8876250
Molecular Function	GO:0120020	cholesterol transfer activity	Mttp	IDA		Mouse	MGI:MGI:6467714|PMID:15897609
Molecular Function	GO:0120020	cholesterol transfer activity	Mttp	IDA		Rat	PMID:15897609|RGD:39458034
Molecular Function	GO:0005319	lipid transporter activity	Mttp	IDA		Mouse	PMID:12072432
Molecular Function	GO:0005319	lipid transporter activity	Mttp	IDA		Rat	PMID:15383310|RGD:1582565
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	MTTP	IDA		Human	PMID:16478722
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	MTTP	IMP		Human	PMID:8876250
Molecular Function	GO:0120019	phosphatidylcholine transfer activity	Mttp	IMP		Rat	PMID:16478722|RGD:39458033
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	MTTP	IDA		Human	PMID:15897609
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	MTTP	IDA		Human	PMID:16478722
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	Mttp	IDA		Mouse	MGI:MGI:6467714|PMID:15897609
Molecular Function	GO:1904121	phosphatidylethanolamine transfer activity	Mttp	IDA		Rat	PMID:15897609|RGD:39458034
Molecular Function	GO:0120014	phospholipid transfer activity	MTTP	IDA		Human	PMID:23475612
Molecular Function	GO:0120014	phospholipid transfer activity	MTTP	IDA		Human	PMID:26224785
Molecular Function	GO:0120014	phospholipid transfer activity	Mttp	IDA		Mouse	MGI:MGI:6706092|PMID:33168624
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:Q4VIT4	Human	PMID:10946006
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P07237	Human	PMID:16478722
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P07237	Human	PMID:23475612
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P04114	Human	PMID:25108285
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P07237	Human	PMID:25108285
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P04114	Human	PMID:26224785
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P07237	Human	PMID:26224785
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:Q4VIT4	Human	PMID:26224785
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:P04114	Human	PMID:27487388
Molecular Function	GO:0005515	protein binding	MTTP	IPI	UniProtKB:Q4VIT4	Human	PMID:27487388
Molecular Function	GO:0005515	protein binding	Mttp	IPI	UniProtKB:Q80XD8	Mouse	MGI:MGI:6706092|PMID:33168624
Molecular Function	GO:0046982	protein heterodimerization activity	MTTP	IDA		Human	PMID:23475612
Molecular Function	GO:0044877	protein-containing complex binding	Mttp	IPI	RGD:3244	Rat	PMID:11830580|RGD:1582567
Molecular Function	GO:0140344	triglyceride transfer activity	MTTP	IDA		Human	PMID:15897609
Molecular Function	GO:0140344	triglyceride transfer activity	MTTP	IDA		Human	PMID:16478722
Molecular Function	GO:0140344	triglyceride transfer activity	MTTP	IDA		Human	PMID:22236406
Molecular Function	GO:0140344	triglyceride transfer activity	MTTP	IDA		Human	PMID:25108285
Molecular Function	GO:0140344	triglyceride transfer activity	MTTP	IMP		Human	PMID:8876250
Molecular Function	GO:0140344	triglyceride transfer activity	Mttp	IDA		Mouse	MGI:MGI:6467715|PMID:16478722
Molecular Function	GO:0140344	triglyceride transfer activity	Mttp	IDA		Mouse	MGI:MGI:6706092|PMID:33168624
Molecular Function	GO:0140344	triglyceride transfer activity	Mttp	IDA		Mouse	MGI:MGI:6467714|PMID:15897609
Molecular Function	GO:0140344	triglyceride transfer activity	Mttp	IDA		Rat	PMID:15897609|RGD:39458034
Molecular Function	GO:0140344	triglyceride transfer activity	Mttp	IDA		Rat	PMID:16478722|RGD:39458033
Cellular Component	GO:0016323	basolateral plasma membrane	Mttp	IDA		Rat	PMID:11830580|RGD:1582567
Cellular Component	GO:0031526	brush border membrane	Mttp	IDA		Rat	PMID:15383310|RGD:1582565
Cellular Component	GO:0005829	cytosol	MTTP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	MTTP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	MTTP	IDA		Human	PMID:16478722
Cellular Component	GO:0005783	endoplasmic reticulum	MTTP	IDA		Human	PMID:22236406
Cellular Component	GO:0005783	endoplasmic reticulum	MTTP	IDA		Human	PMID:23475612
Cellular Component	GO:0005783	endoplasmic reticulum	MTTP	IDA		Human	PMID:26224785
Cellular Component	GO:0005783	endoplasmic reticulum	Mttp	IDA		Mouse	MGI:MGI:6706092|PMID:33168624
Cellular Component	GO:0005794	Golgi apparatus	MTTP	IDA		Human	PMID:16478722
Cellular Component	GO:0005794	Golgi apparatus	Mttp	IDA		Rat	PMID:11830580|RGD:1582567
Cellular Component	GO:0031528	microvillus membrane	Mttp	IDA		Rat	PMID:15383310|RGD:1582565
Cellular Component	GO:0043235	receptor complex	MTTP	IDA		Human	PMID:23382219
Cellular Component	GO:0005791	rough endoplasmic reticulum	Mttp	IDA		Rat	PMID:11830580|RGD:1582567
Cellular Component	GO:0031982	vesicle	Mttp	IDA		Rat	PMID:15383310|RGD:1582565
Biological Process	GO:0042632	cholesterol homeostasis	Mttp	IMP	MGI:MGI:2152201	Mouse	PMID:10713055
Biological Process	GO:0042632	cholesterol homeostasis	Mttp	IEP		Rat	PMID:14972350|RGD:1582566
Biological Process	GO:0007623	circadian rhythm	Mttp	IEP		Mouse	MGI:MGI:5607511|PMID:24353284
Biological Process	GO:0007586	digestion	mttp	IEP		Zfish	PMID:15614773
Biological Process	GO:0051649	establishment of localization in cell	Mttp	IMP	MGI:MGI:2152201	Mouse	PMID:10713055
Biological Process	GO:0006629	lipid metabolic process	Mttp	IDA		Mouse	PMID:12072432
Biological Process	GO:0006629	lipid metabolic process	mttp	IMP	ZFIN:ZDB-MRPHLNO-070118-2	Zfish	PMID:17176039
Biological Process	GO:0006869	lipid transport	Mttp	IDA		Rat	PMID:15383310|RGD:1582565
Biological Process	GO:0006869	lipid transport	mttp	IMP	ZFIN:ZDB-GENO-121114-10	Zfish	PMID:32760060
Biological Process	GO:0006869	lipid transport	mttp	IMP	ZFIN:ZDB-GENO-211208-1	Zfish	PMID:32760060
Biological Process	GO:0042158	lipoprotein biosynthetic process	mttp	IMP		Zfish	PMID:24812437
Biological Process	GO:0042157	lipoprotein metabolic process	Mttp	IMP	MGI:MGI:2152201	Mouse	PMID:10713055
Biological Process	GO:0042157	lipoprotein metabolic process	Mttp	IDA		Rat	PMID:11830580|RGD:1582567
Biological Process	GO:0042953	lipoprotein transport	Mttp	IMP	MGI:MGI:2152201	Mouse	PMID:10713055
Biological Process	GO:0015909	long-chain fatty acid transport	mttp	IMP	ZFIN:ZDB-MRPHLNO-070118-2	Zfish	PMID:17176039
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	Mttp	IDA		Mouse	PMID:27471003
Biological Process	GO:0001579	medium-chain fatty acid transport	mttp	IMP	ZFIN:ZDB-MRPHLNO-070118-2	Zfish	PMID:17176039
Biological Process	GO:0015914	phospholipid transport	MTTP	IDA		Human	PMID:23475612
Biological Process	GO:0015914	phospholipid transport	MTTP	IDA		Human	PMID:26224785
Biological Process	GO:0034377	plasma lipoprotein particle assembly	MTTP	IDA		Human	PMID:16478722
Biological Process	GO:0034377	plasma lipoprotein particle assembly	MTTP	IDA		Human	PMID:23475612
Biological Process	GO:0034377	plasma lipoprotein particle assembly	MTTP	IDA		Human	PMID:26224785
Biological Process	GO:0034377	plasma lipoprotein particle assembly	MTTP	IMP		Human	PMID:8876250
Biological Process	GO:0006497	protein lipidation	Mttp	IDA		Mouse	PMID:12072432
Biological Process	GO:0009306	protein secretion	MTTP	IDA		Human	PMID:16478722
Biological Process	GO:0009306	protein secretion	MTTP	IMP		Human	PMID:23749231
Biological Process	GO:0009306	protein secretion	MTTP	IMP		Human	PMID:8876250
Biological Process	GO:0051592	response to calcium ion	Mttp	IEP		Rat	PMID:16651714|RGD:1625484
Biological Process	GO:0002040	sprouting angiogenesis	mttp	IMP	ZFIN:ZDB-GENO-121113-3	Zfish	PMID:23728425
Biological Process	GO:0002040	sprouting angiogenesis	mttp	IMP	ZFIN:ZDB-GENO-121114-10	Zfish	PMID:22581286
Biological Process	GO:0006641	triglyceride metabolic process	Mttp	IDA		Mouse	PMID:12072432
Biological Process	GO:0034197	triglyceride transport	MTTP	IDA		Human	PMID:22236406
Biological Process	GO:0034197	triglyceride transport	MTTP	IDA		Human	PMID:23475612
Biological Process	GO:0034197	triglyceride transport	MTTP	IMP		Human	PMID:23749231
Biological Process	GO:0034197	triglyceride transport	MTTP	IDA		Human	PMID:25108285
Biological Process	GO:0034197	triglyceride transport	MTTP	IDA		Human	PMID:26224785

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern