Comparative GO Graph (mouse, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Mup1
  • Rat genes LOC259244,LOC259246,LOC298111,LOC500473,Mup4,Mup4-ps6,Mup4l2,Mup5
  • Zfish genes ptgdsb.1,ptgdsb.2,zgc:153704
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mup1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005009	insulin receptor activity	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Molecular Function	GO:0005186	pheromone activity	Mup1	IDA		Mouse	PMID:17935991
Molecular Function	GO:0005550	pheromone binding	Mup1	IDA		Mouse	MGI:MGI:5009190|PMID:11316880
Molecular Function	GO:0005550	pheromone binding	Mup1	IDA		Mouse	PMID:21205906
Molecular Function	GO:0001972	retinoic acid binding	ptgdsb.1	IDA		Zfish	PMID:16616995
Cellular Component	GO:0005829	cytosol	Mup1	IDA		Mouse	MGI:MGI:55715|PMID:6643987
Cellular Component	GO:0005615	extracellular space	Mup1	IDA		Mouse	MGI:MGI:55715|PMID:6643987
Cellular Component	GO:0005615	extracellular space	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Cellular Component	GO:0005615	extracellular space	Mup1	IDA		Mouse	PMID:17935991
Cellular Component	GO:0005615	extracellular space	LOC259246	IDA		Rat	PMID:6886376|RGD:8554344
Cellular Component	GO:0005634	nucleus	Mup1	IDA		Mouse	MGI:MGI:55715|PMID:6643987
Biological Process	GO:0009060	aerobic respiration	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0071240	cellular response to food	Mup1	IEP		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0071396	cellular response to lipid	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0009267	cellular response to starvation	Mup1	IEP		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0071394	cellular response to testosterone stimulus	Mup1	IEP		Mouse	MGI:MGI:55715|PMID:6643987
Biological Process	GO:0071394	cellular response to testosterone stimulus	Mup1	IEP		Mouse	MGI:MGI:55857|PMID:6707444
Biological Process	GO:0006112	energy reserve metabolic process	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0042593	glucose homeostasis	Mup1	IMP		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0031649	heat generation	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0045475	locomotor rhythm	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0070584	mitochondrion morphogenesis	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0045721	negative regulation of gluconeogenesis	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0051055	negative regulation of lipid biosynthetic process	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0010888	negative regulation of lipid storage	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0010628	positive regulation of gene expression	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0010907	positive regulation of glucose metabolic process	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0010907	positive regulation of glucose metabolic process	Mup1	IDA		Mouse	MGI:MGI:3849243|PMID:19258313
Biological Process	GO:0045834	positive regulation of lipid metabolic process	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Mup1	IDA		Mouse	MGI:MGI:3850893|PMID:19336396
Biological Process	GO:0035634	response to stilbenoid	Mup1	IEP		Mouse	MGI:MGI:4943399|PMID:17086191

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern