Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MVD
  • Mouse genes Mvd
  • Rat genes Mvd
  • Zfish genes mvda
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mvd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004163	diphosphomevalonate decarboxylase activity	MVD	IDA		Human	PMID:11792727
Molecular Function	GO:0004163	diphosphomevalonate decarboxylase activity	MVD	IDA		Human	PMID:14680974
Molecular Function	GO:0004163	diphosphomevalonate decarboxylase activity	Mvd	IDA		Rat	PMID:197206|RGD:2316852
Molecular Function	GO:0004163	diphosphomevalonate decarboxylase activity	Mvd	IDA		Rat	PMID:9348097|RGD:2311302
Molecular Function	GO:0030544	Hsp70 protein binding	MVD	IPI	UniProtKB:P38647	Human	PMID:12646231
Molecular Function	GO:0042803	protein homodimerization activity	MVD	IDA		Human	PMID:8626466
Cellular Component	GO:0005829	cytosol	MVD	IDA		Human	PMID:14972328
Cellular Component	GO:0005829	cytosol	Mvd	IDA		Mouse	MGI:MGI:6414993|PMID:12736493
Cellular Component	GO:0005829	cytosol	Mvd	IDA		Rat	PMID:11767099|RGD:729305
Cellular Component	GO:0005782	peroxisomal matrix	Mvd	IDA		Rat	PMID:11767099|RGD:729305
Cellular Component	GO:0005777	peroxisome	Mvd	IDA		Rat	PMID:12081138|RGD:2311301
Biological Process	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	Mvd	IDA		Rat	PMID:197206|RGD:2316852
Biological Process	GO:0008299	isoprenoid biosynthetic process	MVD	IDA		Human	PMID:11792727
Biological Process	GO:0008299	isoprenoid biosynthetic process	MVD	IDA		Human	PMID:14680974
Biological Process	GO:0003334	keratinocyte development	mvda	IMP	ZFIN:ZDB-MRPHLNO-220318-4	Zfish	PMID:34051853
Biological Process	GO:0008284	positive regulation of cell population proliferation	MVD	IMP		Human	PMID:9270019
Biological Process	GO:0045765	regulation of angiogenesis	mvda	IMP	ZFIN:ZDB-MRPHLNO-220318-4	Zfish	PMID:34051853
Biological Process	GO:0009410	response to xenobiotic stimulus	Mvd	IEP		Rat	PMID:14519959|RGD:2311300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern