Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MVP
  • Mouse genes Mvp
  • Rat genes Mvp
  • Zfish genes mvp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mvp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	MVP	IPI	UniProtKB:Q14764	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	MVP	IPI	UniProtKB:Q14764	Human	PMID:24722188
Molecular Function	GO:0042802	identical protein binding	MVP	IPI	UniProtKB:Q14764	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	MVP	IPI	UniProtKB:Q14764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:P28482	Human	PMID:15133037
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q06124	Human	PMID:15133037
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q8NDQ6	Human	PMID:16815308
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:P27695	Human	PMID:18809583
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q53EP0-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q8WUN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MVP	IPI	UniProtKB:Q9H0E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mvp	IPI	UniProtKB:P04150	Rat	PMID:16619302|RGD:8554562
Molecular Function	GO:0005515	protein binding	Mvp	IPI	UniProtKB:P06536	Rat	PMID:16619302|RGD:8554562
Molecular Function	GO:0019901	protein kinase binding	MVP	IPI	UniProtKB:P12931	Human	PMID:16441665
Molecular Function	GO:0019903	protein phosphatase binding	MVP	IDA		Human	PMID:15133037
Cellular Component	GO:0005737	cytoplasm	MVP	IDA		Human	PMID:16441665
Cellular Component	GO:0005856	cytoskeleton	MVP	IDA		Human	PMID:16441665
Cellular Component	GO:0005829	cytosol	MVP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	MVP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	MVP	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	MVP	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	MVP	HDA		Human	PMID:21362503
Cellular Component	GO:0016020	membrane	MVP	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	MVP	IDA		Human	PMID:15133037
Cellular Component	GO:0005634	nucleus	MVP	IDA		Human	PMID:16441665
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MVP	IDA		Human	PMID:16441665
Biological Process	GO:0007420	brain development	mvp	IMP	ZFIN:ZDB-MRPHLNO-121207-18	Zfish	PMID:22566537
Biological Process	GO:0008283	cell population proliferation	Mvp	IMP		Mouse	MGI:MGI:5486560|PMID:15133037
Biological Process	GO:1904888	cranial skeletal system development	mvp	IGI	ZFIN:ZDB-CRISPR-200506-2,ZFIN:ZDB-CRISPR-200506-4	Zfish	PMID:31553903
Biological Process	GO:0038127	ERBB signaling pathway	MVP	IDA		Human	PMID:15133037
Biological Process	GO:0001654	eye development	mvp	IMP	ZFIN:ZDB-MRPHLNO-121207-18	Zfish	PMID:22566537
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	MVP	IDA		Human	PMID:16441665
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	MVP	IDA		Human	PMID:16441665
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	MVP	IDA		Human	PMID:16441665
Biological Process	GO:0031102	neuron projection regeneration	mvp	IMP	ZFIN:ZDB-MRPHLNO-130306-5	Zfish	PMID:23106570
Biological Process	GO:0072376	protein activation cascade	Mvp	IMP		Mouse	MGI:MGI:5486560|PMID:15133037

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern