Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MXD1
  • Mouse genes Mxd1
  • Rat genes Mxd1
  • Zfish genes mxd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mxd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MXD1	IDA		Human	PMID:10723141
Molecular Function	GO:0005515	protein binding	MXD1	IPI	UniProtKB:P61244	Human	PMID:17418410
Molecular Function	GO:0005515	protein binding	MXD1	IPI	UniProtKB:P61244	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	Mxd1	IPI	UniProtKB:Q60520	Mouse	MGI:MGI:79975|PMID:7889570
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MXD1	IDA		Human	PMID:10723141
Cellular Component	GO:0000785	chromatin	MXD1	IDA		Human	PMID:12837246
Cellular Component	GO:0005829	cytosol	MXD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070443	Mad-Max complex	MXD1	IPI		Human	PMID:12553908
Cellular Component	GO:0005739	mitochondrion	MXD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MXD1	IDA		Human	GO_REF:0000052
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MXD1	IDA		Human	PMID:10723141
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MXD1	IDA		Human	PMID:12837246

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern